Literature DB >> 3790076

Intralipid administration induces a lipoprotein lipase-like activity in the livers of starved adult rats.

S Vilaró, M Reina, I Ramírez, M Llobera.   

Abstract

The administration of Intralipid to starved adult rats induces the appearance of lipoprotein lipase (LPL)-like activity in the liver, whereas the so-called hepatic triacylglycerol lipase is unaffected. This LPL-like activity is eluted by 1.5 M-NaCl from heparin-Sepharose columns. This partially purified fraction is inhibited by 1.0 M-NaCl (91%) and by 1.0 mg of protamine sulphate/ml (79%), whereas it is stimulated 69-fold by the presence of 8.0 micrograms of apolipoprotein C-II/ml and inhibited by anti-LPL antibodies. We conclude that Intralipid administration induces the appearance of LPL activity in livers of starved adult rats. Its possible origin is discussed.

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Year:  1986        PMID： 3790076      PMCID： PMC1146816          DOI： 10.1042/bj2360273

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  35 in total

1.  Rat heart lipoprotein lipase.

Authors:  J S Twu; A S Garfinkel; M C Schotz
Journal:  Atherosclerosis       Date:  1975 Nov-Dec       Impact factor: 5.162

2.  Heterogeneity of salt-resistant lipase from human postheparin plasma.

Authors:  C Ehnholm; P K Kinnunen; J K Huttunen
Journal:  FEBS Lett       Date:  1975-04-01       Impact factor: 4.124

3.  The kinetics of the inhibition of lipoprotein lipase by polyanions and polycations.

Authors:  E D KORN
Journal:  J Biol Chem       Date:  1962-11       Impact factor: 5.157

4.  Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase.

Authors:  P K Kinnunen; C Ehnolm
Journal:  FEBS Lett       Date:  1976-06-15       Impact factor: 4.124

5.  A stable, radioactive substrate emulsion for assay of lipoprotein lipase.

Authors:  P Nilsson-Ehle; M C Schotz
Journal:  J Lipid Res       Date:  1976-09       Impact factor: 5.922

6.  Purification and characterization of lipoprotein lipase from human heart.

Authors:  J S Twu; A S Garfinkel; M C Schotz
Journal:  Atherosclerosis       Date:  1976 Jul-Aug       Impact factor: 5.162

7.  Characterization, subcellular localization, and partial purification of a heparin-released triglyceride lipase from rat liver.

Authors:  G Assmann; R M Krauss; D S Fredrickson; R I Levy
Journal:  J Biol Chem       Date:  1973-03-25       Impact factor: 5.157

8.  Separation of molecular species of lipoprotein lipase from adipose tissue.

Authors:  A S Garfinkel; M C Schotz
Journal:  J Lipid Res       Date:  1972-01       Impact factor: 5.922

9.  Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides.

Authors:  P Belfrage; M Vaughan
Journal:  J Lipid Res       Date:  1969-05       Impact factor: 5.922

10.  Mechanism of salt-mediated inhibition of lipoprotein lipase.

Authors:  C J Fielding; P E Fielding
Journal:  J Lipid Res       Date:  1976-05       Impact factor: 5.922
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  7 in total

1.  Lipoprotein lipase activity in neonatal-rat liver cell types.

Authors:  F Burgaya; J Peinado; S Vilaró; M Llobera; I Ramírez
Journal:  Biochem J       Date:  1989-04-01       Impact factor: 3.857

2.  Lipid metabolism during in vitro induction of the lipocyte phenotype in hepatic stellate cells.

Authors:  C P Vicente; R M Guaragna; R Borojevic
Journal:  Mol Cell Biochem       Date:  1997-03       Impact factor: 3.396

3.  Relationship between lipoprotein lipase and peroxisome proliferator-activated receptor-alpha expression in rat liver during development.

Authors:  M Panadero; C Bocos; E Herrera
Journal:  J Physiol Biochem       Date:  2006-09       Impact factor: 4.158

4.  Synthesis of lipoprotein lipase in the liver of newborn rats and localization of the enzyme by immunofluorescence.

Authors:  S Vilaró; M Llobera; G Bengtsson-Olivecrona; T Olivecrona
Journal:  Biochem J       Date:  1988-01-15       Impact factor: 3.857

5.  Lipoprotein lipase modulates net secretory output of apolipoprotein B in vitro. A possible pathophysiologic explanation for familial combined hyperlipidemia.

Authors:  K J Williams; K A Petrie; R W Brocia; T L Swenson
Journal:  J Clin Invest       Date:  1991-10       Impact factor: 14.808

6.  Lipoprotein lipase and hepatic lipase in Wistar and Sprague-Dawley rat tissues. Differences in the effects of gender and fasting.

Authors:  X Galan; M Llobera; I Ramírez
Journal:  Lipids       Date:  1994-05       Impact factor: 1.880

7.  Lipoprotein lipase expression in livers of morbidly obese patients could be responsible for liver steatosis.

Authors:  Eva Pardina; Juan A Baena-Fustegueras; Rafael Llamas; Roberto Catalán; Rosa Galard; Albert Lecube; Jose M Fort; Miquel Llobera; Helena Allende; Víctor Vargas; Julia Peinado-Onsurbe
Journal:  Obes Surg       Date:  2009-03-20       Impact factor: 4.129
  7 in total

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