Literature DB >> 378985

Conditional-lethal deoxyribonucleic acid ligase mutant of Escherichia coli.

J J Dermody, G T Robinson, R Sternglanz.   

Abstract

A new Escherichia coli deoxyribonucleic acid (DNA) ligase mutant has been identified among a collection of temperature-sensitive DNA replication mutants isolated recently (Sevastopoulos, Wehr, and Glaser, Proc. Natl. Acad. Sci. U.S.A. 74:3485-3489, 1977). At the nonpermissive temperature DNA synthesis in the mutant stops rapidly, the DNA is degraded to acid-soluble material, and cell death ensures. This suggests that the mutant may be among the most ligase-deficient strains yet characterized.

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Year:  1979        PMID: 378985      PMCID: PMC216928          DOI: 10.1128/jb.139.2.701-704.1979

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  19 in total

1.  DNA degradation in an amber mutant of Escherichia coli K12 affecting DNA ligase and viability.

Authors:  T Horiuchi; T Sato; T Nagata
Journal:  J Mol Biol       Date:  1975-06-25       Impact factor: 5.469

2.  Nalidixic acid-sensitive and resistant modes of DNA replication in Escherichia coli.

Authors:  J J Dermody; G J Bourguignon; P D Foglesong; R Sternglanz
Journal:  Biochem Biophys Res Commun       Date:  1974-12-23       Impact factor: 3.575

3.  DNA synthesis in strains of Escherichia coli K12 with temperature-sensitive DNA ligase and DNA polymerase I.

Authors:  E B Konrad; P Modrich; I R Lehman
Journal:  J Mol Biol       Date:  1974-11-25       Impact factor: 5.469

4.  Genetic and enzymatic characterization of a conditional lethal mutant of Escherichia coli K12 with a temperature-sensitive DNA ligase.

Authors:  E B Konrad; P Modrich; I R Lehman
Journal:  J Mol Biol       Date:  1973-07-15       Impact factor: 5.469

5.  An amber dna mutant of Escherichia coli K12 affecting DNA ligase.

Authors:  T Nagata; T Horiuchi
Journal:  J Mol Biol       Date:  1974-08-05       Impact factor: 5.469

6.  Enzymatic joining of DNA strands, II. An enzyme-adenylate intermediate in the dpn-dependent DNA ligase reaction.

Authors:  J W Little; S B Zimmerman; C K Oshinsky; M Gellert
Journal:  Proc Natl Acad Sci U S A       Date:  1967-11       Impact factor: 11.205

7.  Genetics and function of DNA ligase in Escherichia coli.

Authors:  M M Gottesman; M L Hicks; M Gellert
Journal:  J Mol Biol       Date:  1973-07-15       Impact factor: 5.469

8.  Enzymatic characterization of a mutant of Escherichia coli with an altered DNA ligase.

Authors:  P Modrich; I R Lehman
Journal:  Proc Natl Acad Sci U S A       Date:  1971-05       Impact factor: 11.205

9.  RNA synthesis initiates in vitro conversion of M13 DNA to its replicative form.

Authors:  W Wickner; D Brutlag; R Schekman; A Kornberg
Journal:  Proc Natl Acad Sci U S A       Date:  1972-04       Impact factor: 11.205

10.  Large-scale automated isolation of Escherichia coli mutants with thermosensitive DNA replication.

Authors:  C G Sevastopoulos; C T Wehr; D A Glaser
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

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  18 in total

1.  Novel bacterial NAD+-dependent DNA ligase inhibitors with broad-spectrum activity and antibacterial efficacy in vivo.

Authors:  Scott D Mills; Ann E Eakin; Ed T Buurman; Joseph V Newman; Ning Gao; Hoan Huynh; Kenneth D Johnson; Sushmita Lahiri; Adam B Shapiro; Grant K Walkup; Wei Yang; Suzanne S Stokes
Journal:  Antimicrob Agents Chemother       Date:  2010-12-28       Impact factor: 5.191

2.  Characterization of an ATP-dependent DNA ligase from the acidophilic archaeon "Ferroplasma acidarmanus" Fer1.

Authors:  Brian R Jackson; Catherine Noble; Manuel Lavesa-Curto; Philip L Bond; Richard P Bowater
Journal:  Extremophiles       Date:  2006-11-30       Impact factor: 2.395

3.  Cloning and functional characterization of an NAD(+)-dependent DNA ligase from Staphylococcus aureus.

Authors:  F S Kaczmarek; R P Zaniewski; T D Gootz; D E Danley; M N Mansour; M Griffor; A V Kamath; M Cronan; J Mueller; D Sun; P K Martin; B Benton; L McDowell; D Biek; M B Schmid
Journal:  J Bacteriol       Date:  2001-05       Impact factor: 3.490

4.  Homology modeling of NAD+-dependent DNA ligase of the Wolbachia endosymbiont of Brugia malayi and its drug target potential using dispiro-cycloalkanones.

Authors:  Nidhi Shrivastava; Jeetendra K Nag; Jyoti Pandey; Rama Pati Tripathi; Priyanka Shah; Mohammad Imran Siddiqi; Shailja Misra-Bhattacharya
Journal:  Antimicrob Agents Chemother       Date:  2015-04-06       Impact factor: 5.191

5.  Polyphosphate accumulation in Escherichia coli in response to defects in DNA metabolism.

Authors:  Luciana Amado; Andrei Kuzminov
Journal:  J Bacteriol       Date:  2009-10-16       Impact factor: 3.490

6.  Unauthorized horizontal spread in the laboratory environment: the tactics of Lula, a temperate lambdoid bacteriophage of Escherichia coli.

Authors:  Ella Rotman; Luciana Amado; Andrei Kuzminov
Journal:  PLoS One       Date:  2010-06-14       Impact factor: 3.240

7.  Construction of hybrid plasmids containing the Escherichia coli uxaB gene: analysis of its regulation and direction of transcription.

Authors:  C Blanco; M Mata-Gilsinger; P Ritzenthaler
Journal:  J Bacteriol       Date:  1983-02       Impact factor: 3.490

8.  In vitro mutagenesis and functional expression in Escherichia coli of a cDNA encoding the catalytic domain of human DNA ligase I.

Authors:  K Kodama; D E Barnes; T Lindahl
Journal:  Nucleic Acids Res       Date:  1991-11-25       Impact factor: 16.971

9.  Trapping and breaking of in vivo nicked DNA during pulsed field gel electrophoresis.

Authors:  Sharik R Khan; Andrei Kuzminov
Journal:  Anal Biochem       Date:  2013-06-14       Impact factor: 3.365

10.  Low-molecular-weight DNA replication intermediates in Escherichia coli: mechanism of formation and strand specificity.

Authors:  Luciana Amado; Andrei Kuzminov
Journal:  J Mol Biol       Date:  2013-07-20       Impact factor: 5.469

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