Literature DB >> 3789699

Bioassay for SF 86-327, a new antifungal agent.

V L Kan, D K Henderson, J E Bennett.   

Abstract

A bioassay with Trichophyton mentagrophytes is described for SF 86-327, an allylamine antifungal agent. SF 86-327 serum concentrations were measured by bioassay in 117 serum sampler from five patients receiving 500 mg/day. The peak, trough, and area under the concentration-time curve were determined after the first dose and at steady state. Drug accumulation occurred with prolonged therapy.

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Year:  1986        PMID： 3789699      PMCID： PMC176498          DOI： 10.1128/AAC.30.4.628

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  2 in total

1.  In-vitro studies with SF 86-327, a new orally active allylamine derivative.

Authors:  S Shadomy; A Espinel-Ingroff; R J Gebhart
Journal:  Sabouraudia       Date:  1985-04

2.  Allylamine derivatives: new class of synthetic antifungal agents inhibiting fungal squalene epoxidase.

Authors:  G Petranyi; N S Ryder; A Stütz
Journal:  Science       Date:  1984-06-15       Impact factor: 47.728
  2 in total
  5 in total

1.  Efficacy of antifungal therapy in a nonneutropenic murine model of zygomycosis.

Authors:  Eric Dannaoui; Johan W Mouton; Jacques F G M Meis; Paul E Verweij
Journal:  Antimicrob Agents Chemother       Date:  2002-06       Impact factor: 5.191

2.  Comparative efficacies of terbinafine and fluconazole in treatment of experimental coccidioidal meningitis in a rabbit model.

Authors:  K N Sorensen; R A Sobel; K V Clemons; L Calderon; K J Howell; P R Irani; D Pappagianis; P L Williams; D A Stevens
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

Review 3.  Terbinafine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in superficial mycoses.

Authors:  J A Balfour; D Faulds
Journal:  Drugs       Date:  1992-02       Impact factor: 9.546

4.  Efficacies of four antifungal agents in experimental murine sporotrichosis.

Authors:  V L Kan; J E Bennett
Journal:  Antimicrob Agents Chemother       Date:  1988-11       Impact factor: 5.191

Review 5.  Analytical methods for determination of terbinafine hydrochloride in pharmaceuticals and biological materials.

Authors:  Basavaiah Kanakapura; Vamsi Krishna Penmatsa
Journal:  J Pharm Anal       Date:  2016-01-25
  5 in total

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