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Literature DB >> 378780

The bactericidal activity of sera of healthy neonates and of newborns with hyperbilirubinaemia to Escherichia coli.

Abstract

Cord and newborn sera were found to possess a significantly decreased in vitro bactericidal activity to Escherichia coli as compared to sera of adult individuals. Hyperbilirubinaemia in neonates suffering from both Rh and ABO incompatibility results in a further significant impairment of the bactericidal activity of their sera in comparison with healthy newborn infants. Exchange transfusion improved considerably the serum bactericidal activity. The possible mechanism of toxic action of unconjugated bilirubin on cells of the immune system is discussed.

Entities: Chemical Disease Gene Species

Mesh：

Year: 1979 PMID： 378780 DOI： 10.1007/bf02927298

Source DB: PubMed Journal: Folia Microbiol (Praha) ISSN： 0015-5632 Impact factor: 2.099

48 in total

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Journal: Arch Dis Child Date: 1975-07 Impact factor: 3.791

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Journal: Proc Soc Exp Biol Med Date: 1961-07

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Journal: Can J Microbiol Date: 1972-10 Impact factor: 2.419

4. The C3-activator system: an alternate pathway of complement activation.

Authors: O Götze; H J Müller-Eberhard
Journal: J Exp Med Date: 1971-09-01 Impact factor: 14.307

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Authors: J R Hobbs; M I Hughes; W Walker
Journal: Lancet Date: 1968-06-29 Impact factor: 79.321

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Journal: J Bacteriol Date: 1968-12 Impact factor: 3.490

7. The virulence for mice of strains of Escherichia coli related to the effects of K antigens on their resistance to phagocytosis and killing by complement.

Authors: C J Howard; A A Glynn
Journal: Immunology Date: 1971-05 Impact factor: 7.397

8. Serum levels of immune globulins in health and disease: a survey.

Authors: E R Stiehm; H H Fudenberg
Journal: Pediatrics Date: 1966-05 Impact factor: 7.124

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Authors: Z Nejedlá
Journal: Pediatrics Date: 1970-01 Impact factor: 7.124

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Authors: K D Tympner; U Ewert; F Neuhaus
Journal: Klin Padiatr Date: 1975-11 Impact factor: 1.349

11 in total

Review 1. The immunosuppressive effects of bilirubin.

Authors: V Vĕtvicka; P Síma; I Miler; M Bilej
Journal: Folia Microbiol (Praha) Date: 1991 Impact factor: 2.099

Review 2. Bactericidal and bacteriolytic activity of serum against gram-negative bacteria.

Authors: P W Taylor
Journal: Microbiol Rev Date: 1983-03

3. The in vitro cytotoxic effect of bilirubin on human lymphocytes and granulocytes.

Authors: I Miler; M Indrová; J Bubeník; J Vondrácek
Journal: Folia Microbiol (Praha) Date: 1985 Impact factor: 2.099

4. The effect of bilirubin on the Fc receptor expression and phagocytic activity of mouse peritoneal macrophages.

Authors: V Vĕtvicka; I Miler; P Síma; L Táborský; L Fornůsek
Journal: Folia Microbiol (Praha) Date: 1985 Impact factor: 2.099

5. Bilirubin inhibits the chemotactic activity of human polymorphonuclear leukocytes in vitro.

Authors: I Miler; J Vondrácek; L Hromádková
Journal: Folia Microbiol (Praha) Date: 1981 Impact factor: 2.099

6. Serum response of Escherichia coli strains causing dyspepsia and urinary tract infection: relation to alpha-hemolysin production and O type.

Authors: L Siegfried; M Kmetová; V Janigová; M Sasinka; V Takácová
Journal: Infect Immun Date: 1995-11 Impact factor: 3.441