Literature DB >> 3783160

Antitumor agents, 82. Cytotoxic sapogenols from Aesculus hippocastanum.

T Konoshima, K H Lee.   

Abstract

Two cytotoxic sapogenols, the new hippocaesculin (1) and the known barringtogenol-C 21-angelate (2), were isolated from the acid hydrolysis product of a crude saponin fraction that was obtained from the fruits of Aesculus hippocastanum. The structures of 1 and 2 were determined from their chemical transformations and spectral data. Compound 1 is either 21-O-angeloyl, 22-O-tigloyl R1-barrigenol, or 21-O-tigloyl, 22-O-angeloyl R1-barrigenol.

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Year:  1986        PMID： 3783160     DOI： 10.1021/np50046a015

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  5 in total

1.  Cytotoxic Barrigenol-like Triterpenoids from an Extract of Cyrilla racemiflora Housed in a Repository.

Authors:  Yulin Ren; Andrew VanSchoiack; Hee-Byung Chai; Michael Goetz; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2015-09-30       Impact factor: 4.050

2.  In vivo anthelmintic activity of crude extracts of Radix angelicae pubescentis, Fructus bruceae, Caulis spatholobi, Semen aesculi, and Semen pharbitidis against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius auratus).

Authors:  You-Tao Liu; Fan Wang; Gao-Xue Wang; Jing Han; Yong Wang; Yong-Hua Wang
Journal:  Parasitol Res       Date:  2010-02-27       Impact factor: 2.289

3.  Antiproliferative triterpenoid saponins of Dodonaea viscosa from the Madagascar dry forest.

Authors:  Shugeng Cao; Peggy Brodie; Martin Callmander; Richard Randrianaivo; Jeremi Razafitsalama; Etienne Rakotobe; Vincent E Rasamison; Karen TenDyke; Yongchun Shen; Edward M Suh; David G I Kingston
Journal:  J Nat Prod       Date:  2009-09       Impact factor: 4.050

4.  Bioactive Triterpenoid Saponins From the Seeds of Aesculus chinensis Bge. var. chekiangensis.

Authors:  Nan Zhang; Shuxiang Wei; Shijie Cao; Qiang Zhang; Ning Kang; Liqin Ding; Feng Qiu
Journal:  Front Chem       Date:  2020-01-23       Impact factor: 5.221

5.  Antiviral escin derivatives from the seeds of Aesculus turbinata Blume (Japanese horse chestnut).

Authors:  Ji Won Kim; Thi-Kim-Quy Ha; Hyomoon Cho; Eunhee Kim; Sang Hee Shim; Jun-Li Yang; Won Keun Oh
Journal:  Bioorg Med Chem Lett       Date:  2017-05-08       Impact factor: 2.823
  5 in total

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