| Literature DB >> 3781925 |
M Yamato, T Takeuchi, H Umezawa, N Sakata, H Hayashi, M Hori.
Abstract
In the biosynthesis of valanimycin, valine is mostly incorporated into the isobutyl moiety of the antibiotic. The alpha-substituted acrylic moiety of valanimycin is derived from alanine. However, a part of alanine is metabolized into valine, thus incorporated also into the isobutyl moiety. Anaerobic conditions and some reducing agents strongly inhibit the biosynthesis.Entities:
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Year: 1986 PMID： 3781925 DOI： 10.7164/antibiotics.39.1263
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649