| Literature DB >> 3777914 |
T R Beam, R P Galask, L T Friedhoff, T B Platt, M A Leitz.
Abstract
The concentrations of aztreonam in human tissues obtained during surgery were measured after a single 2-g intravenous dose. The average concentration in the skeletal muscle, atrial appendage, lung, sternum, pericardial fluid, endometrium, myometrium, fallopian tube, and ovary varied from 3 to 33 micrograms/g (or microgram/ml). These concentrations significantly exceed the MIC for 90% of strains for most members of the family Enterobacteriaceae.Entities:
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Year: 1986 PMID： 3777914 PMCID： PMC180589 DOI： 10.1128/AAC.30.3.505
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191