Literature DB >> 3774261

The in vivo distribution of 99Tcm-HM-PAO in normal man.

D C Costa, P J Ell, I D Cullum, P H Jarritt.   

Abstract

The distribution of 99Tcm-HM-PAO is described in normal man. Since our initial report on the clinical potential of this new radiopharmaceutical in 1984, a number of clinical trials are in progress worldwide. As the tracer has been designed to enable the in vivo assessment of the distribution of cerebral blood flow in man, significant interest in this new 99Tcm-labelled compound can be detected not only in the nuclear medicine practice in general, but in the more specialist areas of medicine such as neurology and psychiatry. In this paper we report findings which should aid in the evaluation of this compound in normal individuals.

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Year:  1986        PMID： 3774261

Source DB:  PubMed          Journal:  Nucl Med Commun        ISSN： 0143-3636            Impact factor:   1.690


  17 in total

1.  Demonstration of human motor cortex activation using SPECT.

Authors:  M S George; H A Ring; D C Costa; K Kouris; P J Ell
Journal:  J Neural Transm Gen Sect       Date:  1992

Review 2.  Radiopharmaceuticals: state of the art.

Authors:  A M Verbruggen
Journal:  Eur J Nucl Med       Date:  1990

3.  Cortical perfusion response to an electrical stimulation of the auditory nerve in profoundly deaf patients: study with technetium-99m hexamethylpropylene amine oxime single photon emission tomography.

Authors:  Y Le Scao; A Robier; J L Baulieu; P Beutter; L Pourcelot
Journal:  Eur J Nucl Med       Date:  1992

4.  RCBF-quantification with 99mTc-HMPAO-SPECT: theory and first results.

Authors:  O Nickel; B Nägele-Wöhrle; P Ulrich; D Eissner; A Roesler; W Grimm; K Hahn
Journal:  Eur J Nucl Med       Date:  1989

5.  Single photon emission computed tomography with 99mTc HM-PAO in the study of focal epilepsy.

Authors:  E Grasso; L Ambrogio; A Cognazzo; P C Gerbino-Promis; P Zagnoni; G F Camuzzini; A Papaleo; F Acchiardi; G Perno
Journal:  Ital J Neurol Sci       Date:  1989-04

6.  Determination of brain death with 123I-IMP and 99mTc-HM-PAO.

Authors:  O Schober; R Galaske; R Heyer
Journal:  Neurosurg Rev       Date:  1987       Impact factor: 3.042

7.  Quantitative analysis of 99mTc-HMPAO kinetics in epilepsy.

Authors:  J T Kuikka; E Länsimies; E O Kuikka
Journal:  Eur J Nucl Med       Date:  1990

8.  Perfusion mapping with Tc-HMPAO in cerebral haematomas.

Authors:  M Rousseaux; M Steinling; D Huglo; A Mazingue; P Barbaste
Journal:  J Neurol Neurosurg Psychiatry       Date:  1991-12       Impact factor: 10.154

9.  Quantification of technetium-99m hexamethylpropylene amine oxime brain uptake in routine clinical practice using calibrated point sources as an external standard: phantom and human studies.

Authors:  A Dobbeleir; R Dierckx
Journal:  Eur J Nucl Med       Date:  1993-08

10.  A study comparing SPECT with CT and MRI after closed head injury.

Authors:  M R Newton; R J Greenwood; K E Britton; M Charlesworth; C C Nimmon; M J Carroll; G Dolke
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-02       Impact factor: 10.154
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