Literature DB >> 3773955

Pharyngeal size in snorers, nonsnorers, and patients with obstructive sleep apnea.

T D Bradley, I G Brown, R F Grossman, N Zamel, D Martinez, E A Phillipson, V Hoffstein.   

Abstract

We measured pharyngeal cross-sectional area and its change with alterations in lung volume in 10 subjects who snored and had obstructive sleep apnea, 6 subjects who snored and did not have obstructive sleep apnea, and 9 subjects who did not snore. Pharyngeal area was measured with use of an acoustic-reflection technique. We found that snorers with and without sleep apnea had a significantly smaller mean (+/- SE) pharyngeal cross-sectional area (4.1 +/- 0.2 and 3.7 +/- 0.9 cm2, respectively) at functional residual capacity than nonsnorers (5.4 +/- 0.5 cm2, P less than 0.025). When lung volume decreased from functional residual capacity to residual volume, both nonsnorers and snorers with sleep apnea had a decrease in pharyngeal area (from 5.4 +/- 0.5 to 4.5 +/- 0.4 cm2 and 4.1 +/- 0.2 to 3.4 +/- 0.2 cm2, respectively), whereas snorers without sleep apnea had no such decrease, suggesting that their pharynxes were less collapsible at low lung volumes. We conclude that snorers with and without sleep apnea have smaller pharyngeal cross-sectional areas than nonsnorers and that snorers with sleep apnea have a further decrease as lung volume falls.

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Year:  1986        PMID: 3773955     DOI: 10.1056/NEJM198611203152105

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


  53 in total

1.  Cigarette smoking behavior and respiratory alterations during sleep in a healthy population.

Authors:  Gonzalo G Casasola; José L Alvarez-Sala; José A Marques; José M F Sánchez-Alarcos; Donald P Tashkin; Domingo Espinós
Journal:  Sleep Breath       Date:  2002-03       Impact factor: 2.816

Review 2.  Sleep. 2: pathophysiology of obstructive sleep apnoea/hypopnoea syndrome.

Authors:  R B Fogel; A Malhotra; D P White
Journal:  Thorax       Date:  2004-02       Impact factor: 9.139

3.  Flow-volume curves in obstructive sleep apnea and snoring.

Authors:  H Rauscher; W Popp; H Zwick
Journal:  Lung       Date:  1990       Impact factor: 2.584

Review 4.  Sleep.7: positive airway pressure therapy for obstructive sleep apnoea/hypopnoea syndrome.

Authors:  P Gordon; M H Sanders
Journal:  Thorax       Date:  2005-01       Impact factor: 9.139

5.  Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism).

Authors:  W S Mezzanotte; D J Tangel; D P White
Journal:  J Clin Invest       Date:  1992-05       Impact factor: 14.808

6.  Volumetric Changes to the Pharynx in Healthy Aging: Consequence for Pharyngeal Swallow Mechanics and Function.

Authors:  Sonja M Molfenter; Charles Lenell; Cathy L Lazarus
Journal:  Dysphagia       Date:  2018-07-23       Impact factor: 3.438

7.  Snoring in children: association with respiratory symptoms and passive smoking.

Authors:  G M Corbo; F Fuciarelli; A Foresi; F De Benedetto
Journal:  BMJ       Date:  1989-12-16

Review 8.  Acoustic reflection: review and clinical applications for sleep-disordered breathing.

Authors:  John S Viviano
Journal:  Sleep Breath       Date:  2002-09       Impact factor: 2.816

9.  Short- and long-term effects of CPAP on upper airway anatomy and collapsibility in OSAH.

Authors:  Luciano Corda; Stefania Redolfi; Luigi Taranto Montemurro; Giuseppe E La Piana; Enrica Bertella; Claudio Tantucci
Journal:  Sleep Breath       Date:  2008-09-25       Impact factor: 2.816

Review 10.  Pathophysiology of sleep apnea.

Authors:  Jerome A Dempsey; Sigrid C Veasey; Barbara J Morgan; Christopher P O'Donnell
Journal:  Physiol Rev       Date:  2010-01       Impact factor: 37.312

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