Literature DB >> 3759657

K-252a, a potent inhibitor of protein kinase C from microbial origin.

H Kase, K Iwahashi, Y Matsuda.   

Abstract

K-252a, a metabolite isolated from the culture broth of Nocardiopsis sp. K-252a, was found to exhibit an extremely potent inhibitory activity on protein kinase C. The IC50 value was 32.9 nM.

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Year:  1986        PMID： 3759657     DOI： 10.7164/antibiotics.39.1059

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  43 in total

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