Literature DB >> 1366997

Identification of indolepyruvic acid as an intermediate of rebeccamycin biosynthesis.

K S Lam1, S Forenza, T W Doyle, C J Pearce.   

Abstract

Experimental evidence is presented to demonstrate that indolepyruvic acid is an intermediate in the rebeccamycin biosynthetic pathway. [3-14C]Indolepyruvic acid was prepared and efficiently incorporated (8%) into rebeccamycin by Saccharothrix aerocolonigenes.

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Year:  1990        PMID： 1366997     DOI： 10.1007/bf01575876

Source DB:  PubMed          Journal:  J Ind Microbiol        ISSN： 0169-4146


  20 in total

1.  STUDIES ON INDOLEPYRUVIC ACID. I. SYNTHESIS AND PAPERCHROMATOGRAPHY.

Authors:  J M KAPER; O GEBHARD; C J VAN DEN BERG; H VELDSTRA
Journal:  Arch Biochem Biophys       Date:  1963-12       Impact factor: 4.013

2.  UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation.

Authors:  I Takahashi; K Asano; I Kawamoto; T Tamaoki; H Nakano
Journal:  J Antibiot (Tokyo)       Date:  1989-04       Impact factor: 2.649

3.  The structures of the novel protein kinase C inhibitors K-252a, b, c and d.

Authors:  T Yasuzawa; T Iida; M Yoshida; N Hirayama; M Takahashi; K Shirahata; H Sano
Journal:  J Antibiot (Tokyo)       Date:  1986-08       Impact factor: 2.649

4.  K-252b, c and d, potent inhibitors of protein kinase C from microbial origin.

Authors:  S Nakanishi; Y Matsuda; K Iwahashi; H Kase
Journal:  J Antibiot (Tokyo)       Date:  1986-08       Impact factor: 2.649

5.  The biosynthesis of indolmycin.

Authors:  U Hornemann; L H Hurley; M K Speedie; H G Floss
Journal:  J Am Chem Soc       Date:  1971-06-16       Impact factor: 15.419

6.  Aminotransferases of Agrobacterium tumefaciens. Transamination between tryptophan and phenylpyruvate.

Authors:  N K Sukanya; C S Vaidyanathan
Journal:  Biochem J       Date:  1964-09       Impact factor: 3.857

7.  Isolation and characterization of tryptophan transaminase and indolepyruvate C-methyltransferase. Enzymes involved in indolmycin biosynthesis in Streptomyces griseus.

Authors:  M K Speedie; U Hornemann; H G Floss
Journal:  J Biol Chem       Date:  1975-10-10       Impact factor: 5.157

8.  Metabolism of tryptophan by Pseudomonas aureofaciens and its relationship to pyrrolnitrin biosynthesis.

Authors:  O Salcher; F Lingens
Journal:  J Gen Microbiol       Date:  1980-12

9.  Biosynthesis of staurosporine, 1. 1H- and 13C-NMR assignments.

Authors:  D Meksuriyen; G A Cordell
Journal:  J Nat Prod       Date:  1988 Sep-Oct       Impact factor: 4.050

10.  UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities.

Authors:  I Takahashi; Y Saitoh; M Yoshida; H Sano; H Nakano; M Morimoto; T Tamaoki
Journal:  J Antibiot (Tokyo)       Date:  1989-04       Impact factor: 2.649
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  3 in total

1.  Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691.

Authors:  Khaled A Shaaban; Sherif I Elshahawi; Xiachang Wang; Jamie Horn; Madan K Kharel; Markos Leggas; Jon S Thorson
Journal:  J Nat Prod       Date:  2015-06-19       Impact factor: 4.050

2.  Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis.

Authors:  Ellen Yeh; Sylvie Garneau; Christopher T Walsh
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-02       Impact factor: 11.205

3.  Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243.

Authors:  Tomoyasu Nishizawa; Courtney C Aldrich; David H Sherman
Journal:  J Bacteriol       Date:  2005-03       Impact factor: 3.490
  3 in total

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