Literature DB >> 3758354

Protein kinase C translocation in relation to proliferative state of C3H 10T1/2 cells.

J Miłoszewska, W Trawicki, P Janik, J Moraczewski, M Przybyszewska, B Szaniawska.   

Abstract

Protein kinase C (PKC) activity of cytosol and membrane fractions of 10T1/2 cells was studied. In cytosol of fast growing cells PKC activity was found in material eluted with 0.150 M NaCl whereas in membrane fractions activity was eluted with 0.065 and 0.150 M NaCl. In the membrane fraction of confluent cells, in contrast to cytosol, very low PKC activity was observed. The translocation pattern of PKC activity eluted with 0.065 M NaCl may be associated with proliferation.

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Year:  1986        PMID： 3758354     DOI： 10.1016/0014-5793(86)80997-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  7 in total

1.  Transcription induction of c-Ki-ras with the tumour promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) in normal and transformed liver cells.

Authors:  S O Chan; S S Wong; D C Yeung
Journal:  Mol Cell Biochem       Date:  1992-11-04       Impact factor: 3.396

2.  Cellular quiescence induced by contact inhibition or serum withdrawal in C3H10T1/2 cells.

Authors:  M Gos; J Miloszewska; P Swoboda; H Trembacz; J Skierski; P Janik
Journal:  Cell Prolif       Date:  2005-04       Impact factor: 6.831

3.  Density-dependent induction of 92-kd type IV collagenase activity in cultures of A431 human epidermoid carcinoma cells.

Authors:  B Xie; C D Bucana; I J Fidler
Journal:  Am J Pathol       Date:  1994-05       Impact factor: 4.307

4.  p21ras and protein kinase C function in distinct and interdependent signaling pathways in C3H 10T1/2 fibroblasts.

Authors:  A Krook; M J Rapoport; S Anderson; H Pross; Y C Zhou; D T Denhardt; T L Delovitch; T Haliotis
Journal:  Mol Cell Biol       Date:  1993-03       Impact factor: 4.272

5.  A phospholipid-stimulated protein kinase from Dictyostelium discoideum.

Authors:  B Jiménez; A Pestaña; M Fernandez-Renart
Journal:  Biochem J       Date:  1989-06-01       Impact factor: 3.857

6.  The effect of phorbol ester treatment on migration of C3H 10T1/2 and BT5C glioma cells: possible application to carcinogenesis.

Authors:  P Janik; B Szaniawska; D Kowalczyk; J Miłoszewska
Journal:  J Cancer Res Clin Oncol       Date:  1994       Impact factor: 4.553

7.  Increased 19 kDa protein phosphorylation and protein kinase C activity in pressure-overload cardiac hypertrophy.

Authors:  B Kwiatkowska-Patzer; K Domańska-Janik
Journal:  Basic Res Cardiol       Date:  1991 Jul-Aug       Impact factor: 17.165
  7 in total

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