Literature DB >> 3755095

Chromosomal localization of human and rat A alpha, B beta, and gamma fibrinogen genes by in situ hybridization.

M W Marino, G M Fuller, F F Elder.   

Abstract

In situ hybridization of radiolabeled fibrinogen cDNAs to human and rat metaphase chromosomes has shown that the genes encoding the A alpha, B beta, and gamma fibrinogen subunits are syntenic in both species. Our data localize the human fibrinogen gene cluster to band q31 on chromosome 4, thereby confirming and extending previous map assignments of these genes in man. We have also assigned these genes to the q31----q34 region of rat chromosome 2. This is the first map assignment of these genes in the rat and also the first report to clearly establish linkage of the B beta subunit gene to the A alpha and gamma genes in this species.

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Year:  1986        PMID： 3755095     DOI： 10.1159/000132248

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  13 in total

1.  Genetic variation at fibrinogen loci and plasma fibrinogen levels.

Authors:  J M Connor; F G Fowkes; J Wood; F B Smith; P T Donnan; G D Lowe
Journal:  J Med Genet       Date:  1992-07       Impact factor: 6.318

2.  Integrative genomics: in silico coupling of rat physiology and complex traits with mouse and human data.

Authors:  Simon N Twigger; Jeff Nie; Victor Ruotti; Jiaming Yu; Dan Chen; Dawei Li; Jed Mathis; Vijay Narayanasamy; Gopal R Gopinath; Dean Pasko; Mary Shimoyama; Norberto De La Cruz; Susan Bromberg; Anne E Kwitek; Howard J Jacob; Peter J Tonellato
Journal:  Genome Res       Date:  2004-04       Impact factor: 9.043

3.  Correlation between genetic and cytogenetic maps of the rat.

Authors:  Y Andoh; T Kuramoto; N Yokoi; T Maihara; K Kitada; T Serikawa
Journal:  Mamm Genome       Date:  1998-04       Impact factor: 2.957

4.  Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma.

Authors:  K H Buetow; J C Murray; J L Israel; W T London; M Smith; M Kew; V Blanquet; C Brechot; A Redeker; S Govindarajah
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

5.  Pairwise linkage analysis of 11 loci on human chromosome 4.

Authors:  J C Murray; K H Buetow; M Smith; L Carlock; A Chakravarti; R F Ferrell; L Gedamu; C Gilliam; R Shiang; C R DeHaven
Journal:  Am J Hum Genet       Date:  1988-03       Impact factor: 11.025

6.  Rat gene mapping using PCR-analyzed microsatellites.

Authors:  T Serikawa; T Kuramoto; P Hilbert; M Mori; J Yamada; C J Dubay; K Lindpainter; D Ganten; J L Guénet; G M Lathrop
Journal:  Genetics       Date:  1992-07       Impact factor: 4.562

7.  Genetic Modulation of Plasma Fibrinogen Concentrations: Possible Importance of Interleukin-6.

Authors: 
Journal:  J Thromb Thrombolysis       Date:  1996       Impact factor: 2.300

8.  Frequency distribution of the G/A alleles of the beta-fibrinogen gene in the Lebanese population.

Authors:  Dina M R Shammaa; Amira S Sabbagh; Ali T Taher; Ghazi S Zaatari; Rami A R Mahfouz
Journal:  Mol Biol Rep       Date:  2007-05-12       Impact factor: 2.316

9.  Map of seven polymorphic markers on rat chromosome 14: linkage conservation with human chromosome 4.

Authors:  E F Remmers; E A Goldmuntz; J M Cash; H Zha; L J Crofford; B Misiewicz-Poltorak; P Mathern; R L Wilder
Journal:  Mamm Genome       Date:  1993       Impact factor: 2.957

10.  Association analysis of genetic polymorphisms of factor V, factor VII and fibrinogen β chain genes with human abdominal aortic aneurysm.

Authors:  Katarzyna Oszajca; Konrad Wroński; Grażyna Janiszewska; Małgorzata Bieńkiewicz; Michał Panek; Jacek Bartkowiak; Janusz Szemraj
Journal:  Exp Ther Med       Date:  2012-06-12       Impact factor: 2.447
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