Literature DB >> 2894759

Pairwise linkage analysis of 11 loci on human chromosome 4.

J C Murray1, K H Buetow, M Smith, L Carlock, A Chakravarti, R F Ferrell, L Gedamu, C Gilliam, R Shiang, C R DeHaven.   

Abstract

New RFLPs are described for INP10 and interleukin 2. The 55 pairwise genetic linkage relationships for these two loci and nine additional loci on the long arm of chromosome 4 (4q) are reported. Fifteen new linkages are established, and new data are added to the four previously reported linkages on 4q. Tight linkage of interleukin 2 (T-cell growth factor), epidermal growth factor, and alcohol dehydrogenase is described. Significant differences were observed between male and female recombination rates. The female rate was estimated to be 1.27 times the male rate. On the basis of these pairwise results, the order for the 11 loci is D4S35-GC-(ALB/AFP)-MT2P1-D4S1-INP10-ADH3-( EGF/IL2)-(FBB/FBA/FBG)-MNS. This preliminary order can serve as a starting point for more detailed multipoint analysis.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2894759      PMCID： PMC1715141     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  42 in total

1.  Linkage of the evolutionarily-related serum albumin and alpha-fetoprotein genes within q11-22 of human chromosome 4.

Authors:  M E Harper; A Dugaiczyk
Journal:  Am J Hum Genet       Date:  1983-07       Impact factor: 11.025

2.  Characterization of complementary deoxyribonucleic acid and genomic deoxyribonucleic acid for the beta chain of human fibrinogen.

Authors:  D W Chung; B G Que; M W Rixon; M Mace; E W Davie
Journal:  Biochemistry       Date:  1983-06-21       Impact factor: 3.162

3.  Linkage between dentinogenesis imperfecta and Gc.

Authors:  S P Ball; P J Cook; M Mars; K E Buckton
Journal:  Ann Hum Genet       Date:  1982-01-01       Impact factor: 1.670

4.  Interstitial deletion 4q and Rieger syndrome.

Authors:  I Ligutić; L Brecević; I Petković; T Kalogjera; Z Rajić
Journal:  Clin Genet       Date:  1981-11       Impact factor: 4.438

5.  Linkage of GLO with HLA and Bf. Effect of population and sex on recombination frequency.

Authors:  L R Weitkamp
Journal:  Tissue Antigens       Date:  1976-05

6.  Fibrinogen gamma chain locus is on chromosome 4 in man.

Authors:  B Olaisen; P Teisberg; T Gedde-Dahl
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

7.  A deletion in chromosome 22 can cause DiGeorge syndrome.

Authors:  A de la Chapelle; R Herva; M Koivisto; P Aula
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

8.  Anterior segment mesenchymal dysgenesis: probable linkage to the MNS blood group on chromosome 4.

Authors:  R E Ferrell; H M Hittner; F L Kretzer; J H Antoszyk
Journal:  Am J Hum Genet       Date:  1982-03       Impact factor: 11.025

Review 9.  Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

Authors:  D Botstein; R L White; M Skolnick; R W Davis
Journal:  Am J Hum Genet       Date:  1980-05       Impact factor: 11.025

10.  Chromosome 15 abnormalities and the Prader-Willi syndrome: a follow-up report of 40 cases.

Authors:  D H Ledbetter; J T Mascarello; V M Riccardi; V D Harper; S D Airhart; R J Strobel
Journal:  Am J Hum Genet       Date:  1982-03       Impact factor: 11.025
View more
  6 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Genetic and physical mapping on chromosome 4 narrows the localization of the gene for facioscapulohumeral muscular dystrophy (FSHD).

Authors:  K A Mills; K H Buetow; Y Xu; T M Ritty; K D Mathews; S E Bodrug; C Wijmenga; I Balazs; J C Murray
Journal:  Am J Hum Genet       Date:  1992-08       Impact factor: 11.025

Review 3.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma.

Authors:  K H Buetow; J C Murray; J L Israel; W T London; M Smith; M Kew; V Blanquet; C Brechot; A Redeker; S Govindarajah
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

5.  A detailed multipoint map of human chromosome 4 provides evidence for linkage heterogeneity and position-specific recombination rates.

Authors:  K H Buetow; R Shiang; P Yang; Y Nakamura; G M Lathrop; R White; J J Wasmuth; S Wood; L D Berdahl; N J Leysens
Journal:  Am J Hum Genet       Date:  1991-05       Impact factor: 11.025

6.  Linkage of aspartylglucosaminuria (AGU) to marker loci on the long arm of chromosome 4.

Authors:  K Grön; P Aula; L Peltonen
Journal:  Hum Genet       Date:  1990-07       Impact factor: 4.132
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.