Literature DB >> 3754364

Neonatal alloimmune thrombocytopenia due to fetomaternal Zwb incompatibility.

C Mueller-Eckhardt, T Becker, M Weisheit, C Witz, S Santoso.   

Abstract

A case of neonatal alloimmune thrombocytopenia due to fetomaternal incompatibility against the platelet-specific antigen Zwb (PlA2) is described. The antibody was of the IgG class and did not fix complement in vitro. Its specificity was established by panel identification and by comparison to a Zwb antiserum. Gene dosage determinations of Zwa antigens on platelets of parents and child revealed that the mother was homozygous Zwa Zwa, while father and child were heterozygous for this antigen.

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Year:  1986        PMID: 3754364     DOI: 10.1111/j.1423-0410.1986.tb04853.x

Source DB:  PubMed          Journal:  Vox Sang        ISSN: 0042-9007            Impact factor:   2.144


  2 in total

1.  Neonatal allo-immune thrombocytopenia due to fetomaternal HPA-1 incompatibility of a homozygous HPA-1a mother and a homozygous HPA-1b father. A case report.

Authors:  R Moser; I Fae; A Neumeister; M Pober; I Mutz; S Panzer
Journal:  Eur J Pediatr       Date:  1994-02       Impact factor: 3.183

2.  New low-frequency platelet glycoprotein polymorphisms associated with neonatal alloimmune thrombocytopenia.

Authors:  Julie A Peterson; Maria L Gitter; Adam Kanack; Brian Curtis; Janice McFarland; Daniel Bougie; Richard Aster
Journal:  Transfusion       Date:  2009-10-10       Impact factor: 3.157

  2 in total

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