Literature DB >> 3753193

Genotoxic effects of ketamine on CHO cells.

S G Adhvaryu, A H Trivedi, K H Jani, R C Vyas, B J Dave.   

Abstract

Ketamine, a non-barbiturate anaesthetic agent, was studied for its genotoxic potential using the SCE assay. It was genotoxic in the in vitro system at concentrations comparable to the plasma levels achieved during steady state anaesthesia. It had no effects on cellular kinetics in CHO cells.

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Year:  1986        PMID： 3753193     DOI： 10.1007/bf00286736

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  9 in total

1.  Sister chromatid exchanges induced by inhaled anesthetics.

Authors:  A E White; S Takehisa; E I Eger; S Wolff; W C Stevens
Journal:  Anesthesiology       Date:  1979-05       Impact factor: 7.892

2.  Changes in serum enzyme levels following ketamine infusions.

Authors:  J W Dundee; J P Fee; J Moore; P D McIlroy; D B Wilson
Journal:  Anaesthesia       Date:  1980-01       Impact factor: 6.955

3.  Lack of mutagenic effects of halothane in mammals in vivo.

Authors:  A Basler; G Röhrborn
Journal:  Anesthesiology       Date:  1981-08       Impact factor: 7.892

4.  Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange.

Authors:  P Perry; H J Evans
Journal:  Nature       Date:  1975-11-13       Impact factor: 49.962

5.  Sister chromatid exchanges in cigarette smokers: effects of halothane, isoflurane or subarachnoid blockade.

Authors:  B Husum; N Valentin; H C Wulf; A Halaburt; E Niebuhr
Journal:  Br J Anaesth       Date:  1985-11       Impact factor: 9.166

6.  Sister chromatid exchanges in lymphocytes in operating room personnel.

Authors:  B Husum; H C Wulf
Journal:  Acta Anaesthesiol Scand       Date:  1980       Impact factor: 2.105

7.  Sister chromatid exchange and growth kinetics in untreated acute leukemia.

Authors:  R Becher; G Zimmer; C G Schmidt
Journal:  Int J Cancer       Date:  1981-02-15       Impact factor: 7.396

8.  Ketamine infusions: pharmacokinetics and clinical effects.

Authors:  J Idvall; I Ahlgren; K R Aronsen; P Stenberg
Journal:  Br J Anaesth       Date:  1979-12       Impact factor: 9.166

9.  Spontaneous and induced sister chromatid exchange frequencies and cell cycle progression in lymphocytes of patients with carcinoma of the uterine cervix.

Authors:  S G Adhvaryu; R C Vyas; B J Dave; A H Trivedi; B N Parikh
Journal:  Cancer Genet Cytogenet       Date:  1985-01-01
  9 in total
  2 in total

1.  In vitro genotoxic effects of areca nut extract and arecoline.

Authors:  B J Dave; A H Trivedi; S G Adhvaryu
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

2.  Genotoxic effects of N-nitrosoketamine and ketamine as assessed by in vitro micronucleus test in Chinese hamster lung fibroblast cell line.

Authors:  Yoshimitsu Toyama; Hidesuke Shimizu; Yuji Suzuki; Yuichi Miyakoshi; Hayato Yoshioka
Journal:  Environ Health Prev Med       Date:  2006-05       Impact factor: 3.674
  2 in total

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