Literature DB >> 3752978

Frequency of aminoglycoside 6'-N-acetyltransferase among Serratia species during increased use of amikacin in the hospital.

T A Larson, C R Garrett, D N Gerding.   

Abstract

The incidence of tobramycin-resistant, gentamicin-susceptible Serratia species at the Minneapolis Veterans Administration Medical Center decreased from an average 42.1 to 2.5% (P less than 0.001) during a 4.5-year period despite the predominant use of amikacin. These organisms were shown to express a 6'-N-acetyltransferase-modifying enzyme (EC 2.3.1.82). Resistance was not shown to be plasmid mediated.

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Year:  1986        PMID： 3752978      PMCID： PMC176460          DOI： 10.1128/AAC.30.1.176

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  R-factor mediated gentamicin resistance: A new enzyme which modifies aminoglycoside antibiotics.

Authors:  R Benveniste; J Davies
Journal:  FEBS Lett       Date:  1971-05-20       Impact factor: 4.124

2.  Plasmids and transposons and their stability and mutability in bacteria isolated during an outbreak of hospital infection.

Authors:  N Datta; V M Hughes; M E Nugent; H Richards
Journal:  Plasmid       Date:  1979-04       Impact factor: 3.466

3.  Plasmid macroevolution in a nosocomial environment: demonstration of a persistent molecular polymorphism and construction of a cladistic phylogeny on the basis of restriction data.

Authors:  S C Lee; D N Gerding; P P Cleary
Journal:  Mol Gen Genet       Date:  1984

4.  Characteristics of Serratia marcescens containing a plasmid coding for gentamicin resistance in nosocomial infections.

Authors:  J F John; W F McNeill
Journal:  J Infect Dis       Date:  1981-06       Impact factor: 5.226

5.  Evidence for a chromosomal site specifying amikacin resistance in multiresistant Serratia marcescens.

Authors:  J F John; W F McNeill; K E Price; P A Kresel
Journal:  Antimicrob Agents Chemother       Date:  1982-04       Impact factor: 5.191

6.  Physical characterization of ten R plasmids obtained from an outbreak of nosocomial Klebsiella pneumoniae infections.

Authors:  P L Sadowski; B C Peterson; D N Gerding; P P Cleary
Journal:  Antimicrob Agents Chemother       Date:  1979-04       Impact factor: 5.191

7.  Enzymatic Adenylylation of Streptomycin and Spectinomycin by R-Factor-Resistant Escherichia coli.

Authors:  R Benveniste; T Yamada; J Davies
Journal:  Infect Immun       Date:  1970-01       Impact factor: 3.441

8.  Aminoglycoside resistance in gram-negative bacilli during increased amikacin use. Comparison of experience in 14 United States hospitals with experience in the Minneapolis Veterans Administration Medical Center.

Authors:  D N Gerding; T A Larson
Journal:  Am J Med       Date:  1985-07-15       Impact factor: 4.965

9.  Comparison of aminoglycoside resistance patterns in Japan, Formosa, and Korea, Chile, and the United States.

Authors:  K Shimizu; T Kumada; W C Hsieh; H Y Chung; Y Chong; R S Hare; G H Miller; F J Sabatelli; J Howard
Journal:  Antimicrob Agents Chemother       Date:  1985-08       Impact factor: 5.191

10.  Amikacin-resistant gram-negative bacilli: correlation of occurrence with amikacin use.

Authors:  J F Levine; M J Maslow; R E Leibowitz; A A Pollock; B A Hanna; S Schaefler; M S Simberkoff; J J Rahal
Journal:  J Infect Dis       Date:  1985-02       Impact factor: 5.226
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  9 in total

1.  Cloning and sequencing of a gene encoding an aminoglycoside 6'-N-acetyltransferase from an R factor of Citrobacter diversus.

Authors:  F C Tenover; D Filpula; K L Phillips; J J Plorde
Journal:  J Bacteriol       Date:  1988-01       Impact factor: 3.490

2.  Unusual aminoglycoside susceptibility pattern and mechanisms of resistance of Serratia marcescens strains from Italy.

Authors:  M Kettner; V Krcméry; P Bonini; P Cichero; C Ossi; V Grazioli
Journal:  Infection       Date:  1991 Jul-Aug       Impact factor: 3.553

3.  Heterogeneity of 6'-N-acetyltransferases of type 4 conferring resistance to amikacin and related aminoglycosides in members of the family Enterobacteriaceae.

Authors:  G Tran Van Nhieu; E Collatz
Journal:  Antimicrob Agents Chemother       Date:  1988-08       Impact factor: 5.191

4.  Three-year survey of amikacin use and aminoglycoside resistance in a general hospital in Belgium.

Authors:  R Vanhoof; J M Hubrechts; H J Nyssen; E Roebben
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1988-04       Impact factor: 3.267

5.  Impact of aminoglycoside cycling in six tertiary intensive care units: prospective longitudinal interventional study.

Authors:  Igor Francetić; Smilja Kalenić; Mirjana Huić; Iveta Mercep; Ksenija Makar-Ausperger; Robert Likić; Viktorija Erdeljić; Vesna Tripković; Petra Simić
Journal:  Croat Med J       Date:  2008-04       Impact factor: 1.351

6.  Aminoglycoside-modifying enzymes in clinical isolates harboring extended-spectrum beta-lactamases.

Authors:  A Fernandez-Rodriguez; R Canton; J C Perez-Diaz; J Martinez-Beltran; J J Picazo; F Baquero
Journal:  Antimicrob Agents Chemother       Date:  1992-11       Impact factor: 5.191

7.  Aminoglycoside resistance and aminoglycoside usage: ten years of experience in one hospital.

Authors:  D N Gerding; T A Larson; R A Hughes; M Weiler; C Shanholtzer; L R Peterson
Journal:  Antimicrob Agents Chemother       Date:  1991-07       Impact factor: 5.191

8.  Aminoglycoside resistance patterns of Serratia marcescens strains of clinical origin.

Authors:  R Coria-Jiménez; C Ortiz-Torres
Journal:  Epidemiol Infect       Date:  1994-02       Impact factor: 2.451

9.  Increased resistance to amikacin in a neonatal unit following intensive amikacin usage.

Authors:  I R Friedland; E Funk; M Khoosal; K P Klugman
Journal:  Antimicrob Agents Chemother       Date:  1992-08       Impact factor: 5.191
  9 in total

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