Literature DB >> 3747720

Skin permeability of various non-steroidal anti-inflammatory drugs in man.

T Yano, A Nakagawa, M Tsuji, K Noda.   

Abstract

The skin permeabilities of a series of eight salicylates and ten non-steroidal anti-inflammatory drugs were investigated in human subjects. The logarithms of % absorption through intact skin and of n-octanol/water partition coefficients (log P) of the test compounds were plotted against one another, and a parabolic relationship was obtained in both compound series.

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Year:  1986        PMID: 3747720     DOI: 10.1016/0024-3205(86)90195-5

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  33 in total

1.  Estimation of molecular linear free energy relationship descriptors. 4. Correlation and prediction of cell permeation.

Authors:  J A Platts; M H Abraham; A Hersey; D Butina
Journal:  Pharm Res       Date:  2000-08       Impact factor: 4.200

2.  Synthesis, in vitro skin permeation studies, and PLS-analysis of new naproxen derivatives.

Authors:  H Weber; U Steimer; R Mannhold; G Cruciani
Journal:  Pharm Res       Date:  2001-05       Impact factor: 4.200

3.  Effect of vehicle pretreatment on the flux, retention, and diffusion of topically applied penetrants in vitro.

Authors:  Catarina Rosado; Sheree E Cross; W John Pugh; Michael S Roberts; Jonathan Hadgraft
Journal:  Pharm Res       Date:  2003-09       Impact factor: 4.200

4.  Spinal disposition and meningeal permeability of local anesthetics.

Authors:  Rozenn Clément; Jean-Marc Malinovsky; Patrice Hildgen; Gilles Dollo; Jean Pierre Estèbe; François Chevanne; Roger Le Verge; Pascal Le Corre
Journal:  Pharm Res       Date:  2004-04       Impact factor: 4.200

5.  Effect of direction (epidermis-to-dermis and dermis-to-epidermis) on the permeation of several chemical compounds through full-thickness skin and stripped skin.

Authors:  Takeshi Oshizaka; Hiroaki Todo; Kenji Sugibayashi
Journal:  Pharm Res       Date:  2012-05-24       Impact factor: 4.200

6.  Skin solubility determines maximum transepidermal flux for similar size molecules.

Authors:  Qian Zhang; Jeffrey E Grice; Peng Li; Owen G Jepps; Guang-Ji Wang; Michael S Roberts
Journal:  Pharm Res       Date:  2009-06-05       Impact factor: 4.200

7.  Nanoparticles do not penetrate human skin--a theoretical perspective.

Authors:  Adam C Watkinson; Annette L Bunge; Jonathan Hadgraft; Majella E Lane
Journal:  Pharm Res       Date:  2013-05-31       Impact factor: 4.200

8.  Topical delivery of hyaluronic acid into skin using SPACE-peptide carriers.

Authors:  Ming Chen; Vivek Gupta; Aaron C Anselmo; John A Muraski; Samir Mitragotri
Journal:  J Control Release       Date:  2013-10-12       Impact factor: 9.776

9.  Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest.

Authors:  Hiromi Baba; Jun-ichi Takahara; Fumiyoshi Yamashita; Mitsuru Hashida
Journal:  Pharm Res       Date:  2015-06-02       Impact factor: 4.200

10.  QSAR analysis of skin permeability of various drugs in man as compared to in vivo and in vitro studies in rodents.

Authors:  E J Lien; H Gao
Journal:  Pharm Res       Date:  1995-04       Impact factor: 4.200

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