Literature DB >> 3741760

The relationship between cisplatin sensitivity and drug uptake into mammalian cells in vitro.

H Eichholtz-Wirth, B Hietel.   

Abstract

Clonogenic survival of HeLa, Chinese hamster and HaK cells after treatment with a range of cisplatin concentrations and exposure times was determined and cellular platinum concentrations were measured by PIXE. It was demonstrated that cisplatin cytotoxicity of the three cell lines varied considerably as a function of drug exposure dose. These differences are related to differential cellular drug uptake.

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Year:  1986        PMID： 3741760      PMCID： PMC2001512          DOI： 10.1038/bjc.1986.168

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  9 in total

1.  A review of platinum complex biochemistry suggests a rationale for combined platinum-radiotherapy.

Authors:  E B Douple; R C Richmond
Journal:  Int J Radiat Oncol Biol Phys       Date:  1979-08       Impact factor: 7.038

2.  DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity.

Authors:  L A Zwelling; T Anderson; K W Kohn
Journal:  Cancer Res       Date:  1979-02       Impact factor: 12.701

3.  DNA cross-linking as an indicator of sensitivity and resistance of mouse L1210 leukemia to cis-diamminedichloroplatinum(II) and L-phenylalanine mustard.

Authors:  L A Zwelling; S Michaels; H Schwartz; P P Dobson; K W Kohn
Journal:  Cancer Res       Date:  1981-02       Impact factor: 12.701

4.  Plasma membrane proteins and glycoproteins from Chinese hamster cells sensitive and resistant to actinomycin D.

Authors:  R H Peterson; J L Biedler
Journal:  J Supramol Struct       Date:  1978

5.  G1 phase chinese hamster V79-379A cells are inherently more sensitive to platinum bound to their DNA than mid S phase or asynchronously treated cells.

Authors:  H N Fraval; J J Roberts
Journal:  Biochem Pharmacol       Date:  1979-05-15       Impact factor: 5.858

6.  DNA cross-linking and cytotoxicity induced by cis-diamminedichloroplatinum(II) in human normal and tumor cell lines.

Authors:  G Laurent; L C Erickson; N A Sharkey; K W Kohn
Journal:  Cancer Res       Date:  1981-09       Impact factor: 12.701

7.  In vivo resistance towards anthracyclines, etoposide, and cis-diamminedichloroplatinum(II).

Authors:  S Seeber; R Osieka; C G Schmidt; W Achterrath; S T Crooke
Journal:  Cancer Res       Date:  1982-11       Impact factor: 12.701

8.  Effects of cis-dichlorodiammineplatinum(II) on human colon carcinoma cells in vitro.

Authors:  J P Bergerat; B Barlogie; B Drewinko
Journal:  Cancer Res       Date:  1979-04       Impact factor: 12.701

9.  Dependence of the cytostatic effect of adriamycin on drug concenration and exposure time in vitro.

Authors:  H Eichholtz-Wirth
Journal:  Br J Cancer       Date:  1980-06       Impact factor: 7.640
  9 in total
  10 in total

1.  A mathematical model for cisplatin cellular pharmacodynamics.

Authors:  Ardith W El-Kareh; Timothy W Secomb
Journal:  Neoplasia       Date:  2003 Mar-Apr       Impact factor: 5.715

2.  Sensitization of C6 glioma to carboplatin cytotoxicity by hyperthermia and thymidine.

Authors:  J D Cohen; H I Robins; M J Javid
Journal:  J Neurooncol       Date:  1990-08       Impact factor: 4.130

Review 3.  Mechanisms of cellular resistance to cisplatin.

Authors:  G A Hospers; N H Mulder; E G De Vries
Journal:  Med Oncol Tumor Pharmacother       Date:  1988

Review 4.  Resistance to cisplatin and analogues: mechanisms and potential clinical implications.

Authors:  A de Graeff; R J Slebos; S Rodenhuis
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

Review 5.  Role of copper transporters in platinum resistance.

Authors:  Deepak Kilari; Elizabeth Guancial; Eric S Kim
Journal:  World J Clin Oncol       Date:  2016-02-10

6.  Short-term cis-diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells.

Authors:  S C Mann; P A Andrews; S B Howell
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

7.  Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined "Complementary Lethality".

Authors:  Mateusz Rytelewski; Peter J Ferguson; Saman Maleki Vareki; Rene Figueredo; Mark Vincent; James Koropatnick
Journal:  Mol Ther Nucleic Acids       Date:  2013-03-12       Impact factor: 10.183

8.  An in vitro study comparing the cytotoxicity of three platinum complexes with regard to the effect of thiol depletion.

Authors:  E Smith; A P Brock
Journal:  Br J Cancer       Date:  1988-06       Impact factor: 7.640

9.  Reduced drug accumulation as a major mechanism of acquired resistance to cisplatin in a human ovarian carcinoma cell line: circumvention studies using novel platinum (II) and (IV) ammine/amine complexes.

Authors:  S Y Loh; P Mistry; L R Kelland; G Abel; K R Harrap
Journal:  Br J Cancer       Date:  1992-12       Impact factor: 7.640

10.  Interactions of doxorubicin and cis-platin in squamous carcinoma cells in culture.

Authors:  N Kohno; T Ohnuma; M Kaneko; J F Holland
Journal:  Br J Cancer       Date:  1988-09       Impact factor: 7.640
  10 in total

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