Literature DB >> 3045443

Mechanisms of cellular resistance to cisplatin.

G A Hospers1, N H Mulder, E G De Vries.   

Abstract

Treatment of cancer patients often fails because of the resistance in the tumor to chemotherapeutic drugs. A better understanding of mechanisms which are active in resistant cells might lead to measures to circumvent the resistance. This review deals with the mechanisms of action of cisplatin (CDDP) and the various causes for CDDP resistance in the tumor cells. Also, possibilities to circumvent CDDP resistance in vitro and in vivo are presented.

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Year:  1988        PMID： 3045443     DOI： 10.1007/BF02986437

Source DB:  PubMed          Journal:  Med Oncol Tumor Pharmacother        ISSN： 0736-0118


  47 in total

1.  Chemical reactivity of monofunctional platinum-DNA adducts.

Authors:  J L Butour; N P Johnson
Journal:  Biochemistry       Date:  1986-08-12       Impact factor: 3.162

Review 2.  5-Methylcytosine in eukaryotic DNA.

Authors:  M Ehrlich; R Y Wang
Journal:  Science       Date:  1981-06-19       Impact factor: 47.728

3.  Carrier-dependent and carrier-independent transport of anti-cancer alkylating agents.

Authors:  J E Byfield; P M Calabro-Jones
Journal:  Nature       Date:  1981-11-19       Impact factor: 49.962

4.  Action of hydrolyzed cisplatin and some analogs on microtubule protein polymerization in vitro.

Authors:  V Peyrot; C Briand; A Crevat; D Braguer; A M Chauvet-Monges; J C Sari
Journal:  Cancer Treat Rep       Date:  1983 Jul-Aug

5.  Interaction of cis-diamminedichloroplatinum (II) to chromatin. Specificity of the drug distribution.

Authors:  M Foka; J Paoletti
Journal:  Biochem Pharmacol       Date:  1986-10-01       Impact factor: 5.858

6.  Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues.

Authors:  B C Behrens; T C Hamilton; H Masuda; K R Grotzinger; J Whang-Peng; K G Louie; T Knutsen; W M McKoy; R C Young; R F Ozols
Journal:  Cancer Res       Date:  1987-01-15       Impact factor: 12.701

7.  Induction and repair of DNA cross-links in chinese hamster ovary cells treated with various platinum coordination compounds in relation to platinum binding to DNA, cytotoxicity, mutagenicity, and antitumor activity.

Authors:  A C Plooy; M van Dijk; P H Lohman
Journal:  Cancer Res       Date:  1984-05       Impact factor: 12.701

8.  Quenching of DNA:platinum(II) monoadducts as a possible mechanism of resistance to cis-diamminedichloroplatinum(II) in L1210 cells.

Authors:  K Micetich; L A Zwelling; K W Kohn
Journal:  Cancer Res       Date:  1983-08       Impact factor: 12.701

9.  Effect of cisplatin on the plasma membrane phosphatase activities in ascites sarcoma-180 cells: a cytochemical study.

Authors:  S K Aggarwal; I Niroomand-Rad
Journal:  J Histochem Cytochem       Date:  1983-02       Impact factor: 2.479

10.  The relationship between cisplatin sensitivity and drug uptake into mammalian cells in vitro.

Authors:  H Eichholtz-Wirth; B Hietel
Journal:  Br J Cancer       Date:  1986-08       Impact factor: 7.640
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  8 in total

Review 1.  New clues for platinum antitumor chemistry: kinetically controlled metal binding to DNA.

Authors:  Jan Reedijk
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-24       Impact factor: 11.205

2.  Cross-resistance to UV radiation of a cisplatin-resistant human cell line: overexpression of cellular factors that recognize UV-modified DNA.

Authors:  C C Chao; S L Huang; H M Huang; S Lin-Chao
Journal:  Mol Cell Biol       Date:  1991-04       Impact factor: 4.272

3.  Damage-recognition proteins as a potential indicator of DNA-damage-mediated sensitivity or resistance of human cells to ultraviolet radiation.

Authors:  C C Chao
Journal:  Biochem J       Date:  1992-02-15       Impact factor: 3.857

4.  Repair synthesis by human cell extracts in cisplatin-damaged DNA is preferentially determined by minor adducts.

Authors:  P Calsou; P Frit; B Salles
Journal:  Nucleic Acids Res       Date:  1992-12-11       Impact factor: 16.971

5.  Identification of inducible damage-recognition proteins that are overexpressed in HeLa cells resistant to cis-diamminedichloroplatinum (II).

Authors:  C C Chao; S L Huang; L Y Lee; S Lin-Chao
Journal:  Biochem J       Date:  1991-08-01       Impact factor: 3.857

6.  Enhancement of cisplatin (DDP) antitumor activity by 3-aminobenzamide in rat ovarian tumors sensitive and resistant to DDP in vivo.

Authors:  G Chen; W J Zeller
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

7.  Correlation of the in vitro cytotoxicity of ethyldeshydroxysparsomycin and cisplatin with the in vivo antitumour activity in murine L1210 leukaemia and two resistant L1210 subclones.

Authors:  H P Hofs; D J Wagener; V de Valk-Bakker; H van Rennes; A J van Zeist; L A van den Broek; H C Ottenheijm
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

Review 8.  Modulation of cis-diamminedichloroplatinum(II) resistance: a review.

Authors:  H Timmer-Bosscha; N H Mulder; E G de Vries
Journal:  Br J Cancer       Date:  1992-08       Impact factor: 7.640
  8 in total

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