| Literature DB >> 3740412 |
J V Staros, R W Wright, D M Swingle.
Abstract
Water-soluble carbodiimides are frequently employed in coupling or conjugation reactions, e.g., to link a peptide immunogen to a carrier protein. However, their utility is limited by low coupling yields obtained under some conditions. We have found that addition of N-hydroxysulfosuccinimide to such reactions can greatly enhance the yields obtained.Entities:
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Year: 1986 PMID： 3740412 DOI： 10.1016/0003-2697(86)90176-4
Source DB: PubMed Journal: Anal Biochem ISSN： 0003-2697 Impact factor: 3.365