Literature DB >> 3729354

Antimicrobial spectrum of Ro 15-8074/001, a new oral cephalosporin.

M G Thomas, S D Lang.   

Abstract

The activity of Ro 15-8074/001 was compared with that of cefaclor, amoxicillin-clavulanic acid, trimethoprim-sulfamethoxazole, norfloxacin, and ceftriaxone against 225 clinical isolates. It was more active than cefaclor, amoxicillin-clavulanic acid, and trimethoprim-sulfamethoxazole against members of the family Enterobacteriaceae and Haemophilus influenzae and had activity similar to that of cefaclor against nonenterococcal streptococci. It was not usefully active against Pseudomonas aeruginosa, Streptococcus faecalis, or most isolates of staphylococci.

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Year:  1986        PMID： 3729354      PMCID： PMC284189          DOI： 10.1128/AAC.29.5.945

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  2 in total

1.  In vitro activity of Ro 15-8074, a new oral cephalosporin, against Neisseria gonorrhoeae.

Authors:  W S Ng; P Y Chau; Y K Leung; P C Wong
Journal:  Antimicrob Agents Chemother       Date:  1985-09       Impact factor: 5.191

2.  In-vitro activity of Ro-15-8074, a new oral cephalosporin.

Authors:  M Peeters; P Piot
Journal:  J Antimicrob Chemother       Date:  1985-10       Impact factor: 5.790
  2 in total
  6 in total

1.  Penetration of cefazolin, ceftriaxone, cefoperazone, and ceftazidime into human gallbladder tissue and bile.

Authors:  S A Berger; Y Levy; A Halevy; A Gorea; R Orda
Journal:  World J Surg       Date:  1988-10       Impact factor: 3.352

2.  In vitro activity of the two new oral cephalosporins RO 15-8074 and RO 19-5247.

Authors:  E Stobberingh; A W Houben; C P van Boven
Journal:  Eur J Clin Microbiol       Date:  1987-08       Impact factor: 3.267

Review 3.  Cefetamet pivoxil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  H M Bryson; R N Brogden
Journal:  Drugs       Date:  1993-04       Impact factor: 9.546

Review 4.  Cefetamet pivoxil clinical pharmacokinetics.

Authors:  R A Blouin; K Stoeckel
Journal:  Clin Pharmacokinet       Date:  1993-09       Impact factor: 6.447

5.  In vitro activity of cefetamet (Ro 15-8074).

Authors:  H Mittermayer
Journal:  Eur J Clin Microbiol       Date:  1986-10       Impact factor: 3.267

6.  Comparative in vitro antibacterial activities of two new oral cephalosporins, ceftetrame (Ro 19-5247) and cefetamet (Ro 15-8074).

Authors:  P Y Chau; Y K Leung; W W Ng; K Arnold
Journal:  Antimicrob Agents Chemother       Date:  1987-03       Impact factor: 5.191
  6 in total

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