Literature DB >> 3725217

Effects of L-cocaine on local cerebral glucose utilization in the rat.

E D London, G Wilkerson, S R Goldberg, M E Risner.   

Abstract

The 2-deoxy-D-[l-14C]glucose method was used to map the in vivo metabolic response (local cerebral glucose utilization. LCGU) to L-cocaine in the rat brain. Injections of L-cocaine HCl (30 mg/kg, i.p.) selectively enhanced LCGU in 5 out of 56 brain regions that were examined (caudate-putamen, globus pallidus, substantia nigra pars reticulata, subthalamic nucleus, cerebellar vermis), but 10 or 30 mg/kg L-cocaine reduced LCGU in the habenula. In general, the acute effects of L-cocaine on LCGU resembled previously reported effects of D-amphetamine and apomorphine.

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Year:  1986        PMID： 3725217     DOI： 10.1016/0304-3940(86)90232-6

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  13 in total

1.  Imaging cocaine-induced changes in the mesocorticolimbic dopaminergic system of conscious rats.

Authors:  Marcelo Febo; Annabell C Segarra; Jeffrey R Tenney; Mathew E Brevard; Timothy Q Duong; Craig F Ferris
Journal:  J Neurosci Methods       Date:  2004-10-30       Impact factor: 2.390

2.  Fos after single and repeated self-administration of cocaine and saline in the rat: emphasis on the Basal forebrain and recalibration of expression.

Authors:  Daniel S Zahm; Mary L Becker; Alexander J Freiman; Sara Strauch; Beth Degarmo; Stefanie Geisler; Gloria E Meredith; Michela Marinelli
Journal:  Neuropsychopharmacology       Date:  2010-01       Impact factor: 7.853

3.  Limbic activation during cue-induced cocaine craving.

Authors:  A R Childress; P D Mozley; W McElgin; J Fitzgerald; M Reivich; C P O'Brien
Journal:  Am J Psychiatry       Date:  1999-01       Impact factor: 18.112

4.  Chronic cannabinoid administration to periadolescent rats modulates the metabolic response to acute cocaine in the adult brain.

Authors:  Alejandro Higuera-Matas; Maria Luisa Soto-Montenegro; Gonzalo L Montoya; Verónica García-Vázquez; Javier Pascau; Miguel Miguéns; Nuria Del Olmo; Juan José Vaquero; Carmen García-Lecumberri; Manuel Desco; Emilio Ambrosio
Journal:  Mol Imaging Biol       Date:  2011-06       Impact factor: 3.488

5.  Functional consequences of acute cocaine treatment depend on route of administration.

Authors:  L J Porrino
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

6.  Lateral Habenula Involvement in Impulsive Cocaine Seeking.

Authors:  Agustin Zapata; Eun-Kyung Hwang; Carl R Lupica
Journal:  Neuropsychopharmacology       Date:  2016-12-27       Impact factor: 7.853

7.  Patterns of functional activity associated with cocaine self-administration in the rat change over time.

Authors:  Darrel J Macey; Wendy N Rice; Cory S Freedland; Christopher T Whitlow; Linda J Porrino
Journal:  Psychopharmacology (Berl)       Date:  2003-12-11       Impact factor: 4.530

8.  Metabolic mapping of the effects of intravenous methamphetamine administration in freely moving rats.

Authors:  F E Pontieri; A M Crane; L S Seiden; M S Kleven; L J Porrino
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

9.  Cerebellar lingula size and experiential risk factors associated with high levels of alcohol and drug use in young adults.

Authors:  Carl M Anderson; Keren Rabi; Scott E Lukas; Martin H Teicher
Journal:  Cerebellum       Date:  2010-06       Impact factor: 3.847

10.  Antagonism of cocaine's stimulant effects on local cerebral glucose utilization by the preferential autoreceptor antagonist (+)-AJ 76.

Authors:  B L Casey; C A Ray; M F Piercey
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575
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