Literature DB >> 3713452

The role of delta superinfection in acute exacerbations of chronic type B hepatitis.

C M Chu, P Farci, Y F Liaw, A Balestrieri, H C Thomas.   

Abstract

Serum specimens collected from patients with chronic type B hepatitis during their acute exacerbations were studied with radioimmunoassay for serological markers of delta (delta) agent infection. Serum delta antigen was negative in all 56 hepatitis B e antigen (HBeAg)-positive and 25 anti-HBe-positive acute exacerbations. Two (3.6%) HBeAg-positive and five (20%) anti-HBe-positive acute exacerbations were found to be positive for both IgG anti-delta and IgM anti-delta. The incidence in anti-HBe-positive patients was significantly higher than in HBeAg-positive patients. These results indicated that some of the acute exacerbations, particularly in anti-HBe-positive phase, could be attributed to delta-superinfection. However, acute exacerbations preceding HBeAg/anti-HBe seroconversion were not associated with delta-superinfection.

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Year:  1986        PMID： 3713452     DOI： 10.1111/j.1600-0676.1986.tb00264.x

Source DB:  PubMed          Journal:  Liver        ISSN： 0106-9543


  4 in total

1.  Immunohistochemical research on HDV infection in Chinese patients with chronic liver disease.

Authors:  Y Y Zhang; L J Hao; M Rizzetto; F Bonino; G Verme
Journal:  J Tongji Med Univ       Date:  1989

2.  Etiology of acute exacerbation in patients with severe chronic active hepatitis by in situ HBVDNA hybridization technique.

Authors:  Y Y Zhang; Y K Wang; H Q Sheng; L Li; L J Hao; Y D Zhang; G Z Hou
Journal:  J Tongji Med Univ       Date:  1990

3.  The aetiology of acute hepatitis in Taiwan: acute hepatitis superimposed on HBsAg carrier state as the main aetiology of acute hepatitis in areas with high HBsAg carrier rate.

Authors:  C M Chu; I S Sheen; Y F Liaw
Journal:  Infection       Date:  1988 Jul-Aug       Impact factor: 3.553

4.  Prevalence and significance of intrahepatic hepatitis delta virus antigen expression in HBeAg-negative patients with chronic type-B hepatitis in Taiwan.

Authors:  C M Chu; W C Shyu; Y F Liaw
Journal:  Dig Dis Sci       Date:  1989-12       Impact factor: 3.199
  4 in total

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