Literature DB >> 2547981

Immunohistochemical research on HDV infection in Chinese patients with chronic liver disease.

Y Y Zhang, L J Hao, M Rizzetto, F Bonino, G Verme.   

Abstract

The prevalence of HDAg in the liver of Chinese patients with chronic hepatitis and hepatocellular carcinoma was determined by using direct immunofluorescence and immunoperoxidase. Six patients (6.3%) out of 95 HBsAg carriers with inflammatory liver disease and neoplasia were found to be HDAg positive. HDAg was shown in the liver of 6 patients (7.6%) among 79 patients with chronic hepatitis. The relative frequency of HDAg in cirrhosis-B, chronic active hepatitis B and chronic persistent hepatitis B was 14.3%, 7.1% and 5.9% respectively. These results suggest that a sizeable number of HBsAg carriers are superinfected with HDV. In view of the large amount of HBV carriers in China, the relative minor but distinct presence of HDV poses an important community health problem.

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Mesh：

Year:  1989        PMID： 2547981     DOI： 10.1007/BF02933735

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN： 0257-716X


  9 in total

1.  Antibodies to hepatitis delta virus cannot be detected in carriers of hepatitis B surface antigen in Wuhan area (PR China).

Authors:  K Gmelin; L Theilmann; R Bernhardt; B Kommerell; F Deinhardt; M Roggendorf; L J Hao
Journal:  J Tongji Med Univ       Date:  1986

2.  Prevalence of hepatitis delta virus infection in different provinces of China.

Authors:  M Roggendorf; K Mai; G Thian; M Hu; C Zhuang; K Gmelin; R Bernhardt; F Deinhardt
Journal:  Prog Clin Biol Res       Date:  1987

3.  The role of delta superinfection in acute exacerbations of chronic type B hepatitis.

Authors:  C M Chu; P Farci; Y F Liaw; A Balestrieri; H C Thomas
Journal:  Liver       Date:  1986-02

4.  [Preliminary study of delta-agent in liver tissue of patients with virus hepatitis B].

Authors:  L J Hao; Y Y Zhang
Journal:  Acta Acad Med Wuhan       Date:  1985

5.  Prevalence of delta agent among Chinese in Taiwan and Los Angeles.

Authors:  S Govindarajan; S D Lee; M J Tong; Y T Tsai; K J Lo
Journal:  J Med Virol       Date:  1984       Impact factor: 2.327

6.  Epidemiology of HBV-associated delta agent: geographical distribution of anti-delta and prevalence in polytransfused HBsAg carriers.

Authors:  M Rizzetto; R H Purcell; J L Gerin
Journal:  Lancet       Date:  1980-06-07       Impact factor: 79.321

7.  The delta agent.

Authors:  M Rizzetto
Journal:  Hepatology       Date:  1983 Sep-Oct       Impact factor: 17.425

8.  Delta agent infection in patients with chronic liver diseases and hepatocellular carcinoma--an infrequent finding in Taiwan.

Authors:  D S Chen; M Y Lai; J L Sung
Journal:  Hepatology       Date:  1984 May-Jun       Impact factor: 17.425

9.  Chronic hepatitis in carriers of hepatitis B surface antigen, with intrahepatic expression of the delta antigen. An active and progressive disease unresponsive to immunosuppressive treatment.

Authors:  M Rizzetto; G Verme; S Recchia; F Bonino; P Farci; S Aricò; R Calzia; A Picciotto; M Colombo; H Popper
Journal:  Ann Intern Med       Date:  1983-04       Impact factor: 25.391
  9 in total
  1 in total

1.  Etiology of acute exacerbation in patients with severe chronic active hepatitis by in situ HBVDNA hybridization technique.

Authors:  Y Y Zhang; Y K Wang; H Q Sheng; L Li; L J Hao; Y D Zhang; G Z Hou
Journal:  J Tongji Med Univ       Date:  1990
  1 in total

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