Literature DB >> 3712437

Elongation factor Tu localized on the exterior surface of the small ribosomal subunit.

J A Langer, J A Lake.   

Abstract

Protein synthesis elongation factor Tu has been mapped on the surface of the ribosome by immunoelectron microscopy. The EF-Tu binding site is located near the concave portion of the small subunit at the level of the neck and extends 60 to 70 A above and below the neck. The binding site is present on the side of the subunit opposite the platform, i.e. on the exterior subunit surface. This EF-Tu site differs from that found for elongation factor G in that the EF-Tu site is significantly more exposed to the cytoplasm.

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Year:  1986        PMID： 3712437     DOI： 10.1016/0022-2836(86)90339-6

Source DB:  PubMed          Journal:  J Mol Biol        ISSN： 0022-2836            Impact factor:   5.469


  8 in total

1.  A ribosomal ambiguity mutation in the 530 loop of E. coli 16S rRNA.

Authors:  M O'Connor; H U Göringer; A E Dahlberg
Journal:  Nucleic Acids Res       Date:  1992-08-25       Impact factor: 16.971

2.  Localization of an oligodeoxynucleotide complementing 16S ribosomal RNA residues 520-531 on the small subunit of Escherichia coli ribosomes: electron microscopy of ribosome-cDNA-antibody complexes.

Authors:  L S Lasater; L Montesano-Roditis; P A Cann; D G Glitz
Journal:  Nucleic Acids Res       Date:  1990-02-11       Impact factor: 16.971

3.  A mutation in the 530 loop of Escherichia coli 16S ribosomal RNA causes resistance to streptomycin.

Authors:  P Melançon; C Lemieux; L Brakier-Gingras
Journal:  Nucleic Acids Res       Date:  1988-10-25       Impact factor: 16.971

4.  Labeling the peptidyltransferase center of the Escherichia coli ribosome with photoreactive tRNA(Phe) derivatives containing azidoadenosine at the 3' end of the acceptor arm: a model of the tRNA-ribosome complex.

Authors:  J Wower; S S Hixson; R A Zimmermann
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

5.  Evidence for functional interaction between elongation factor Tu and 16S ribosomal RNA.

Authors:  T Powers; H F Noller
Journal:  Proc Natl Acad Sci U S A       Date:  1993-02-15       Impact factor: 11.205

6.  Covalent cross-linking of poly(A) to Escherichia coli ribosomes, and localization of the cross-link site within the 16S RNA.

Authors:  W Stiege; K Stade; D Schüler; R Brimacombe
Journal:  Nucleic Acids Res       Date:  1988-03-25       Impact factor: 16.971

7.  Assembly of the Escherichia coli 30S ribosomal subunit reveals protein-dependent folding of the 16S rRNA domains.

Authors:  V Mandiyan; S J Tumminia; J S Wall; J F Hainfeld; M Boublik
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-15       Impact factor: 11.205

8.  Alterations in ribosomal protein RPS28 can diversely affect translational accuracy in Saccharomyces cerevisiae.

Authors:  R A Anthony; S W Liebman
Journal:  Genetics       Date:  1995-08       Impact factor: 4.562
  8 in total

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