Literature DB >> 3712040

Efficient stereospecific synthesis of no-carrier-added 2-[18F]-fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution.

K Hamacher, H H Coenen, G Stöcklin.   

Abstract

An aminopolyether mediated synthesis of fluorine-18 (18F) 2-fluoro-2-deoxy-D-glucose (FDG) has been developed. The nucleophilic fluorination with accelerator-produced [18F]fluoride works at the no-carrier-added level and gives epimerically pure 2-18FDG with an uncorrected radiochemical yield of a maximum 50% in a synthesis time of approximately 50 min from EOB.

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Year:  1986        PMID： 3712040

Source DB:  PubMed          Journal:  J Nucl Med        ISSN： 0161-5505            Impact factor:   10.057


  261 in total

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Journal:  Hum Brain Mapp       Date:  2000-05       Impact factor: 5.038

2.  FDG-PET for preoperative differential diagnosis between benign and malignant soft tissue masses.

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3.  Independent prognostic value of pre-treatment 18-FDG-PET in high-grade gliomas.

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Journal:  J Neurooncol       Date:  2011-12-15       Impact factor: 4.130

4.  Exercise four hour redistribution thallium-201 single photon emission computed tomography and exercise induced ST segment elevation in detecting the viable myocardium in patients with acute myocardial infarction.

Authors:  H Yamagishi; K Akioka; M Takagi; A Tanaka; K Takeuchi; J Yoshikawa; H Ochi
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5.  Exercise training improves insulin-stimulated myocardial glucose uptake in patients with dilated cardiomyopathy.

Authors:  Kira Q Stolen; Jukka Kemppainen; Kari K Kalliokoski; Matti Luotolahti; Tapio Viljanen; Pirjo Nuutila; Juhani Knuuti
Journal:  J Nucl Cardiol       Date:  2003 Sep-Oct       Impact factor: 5.952

6.  Immediate effects of risperidone on cerebral activity in healthy subjects: a comparison with subjects with first-episode schizophrenia.

Authors:  Carol J Lane; Elton T C Ngan; Lakshmi N Yatham; Tom J Ruth; Peter F Liddle
Journal:  J Psychiatry Neurosci       Date:  2004-01       Impact factor: 6.186

7.  Accuracy of image fusion of normal upper abdominal organs visualized with PET/CT.

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Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-01-25       Impact factor: 9.236

8.  One-step (18)F-labeling of peptides for positron emission tomography imaging using the SiFA methodology.

Authors:  Carmen Wängler; Sabrina Niedermoser; Joshua Chin; Katy Orchowski; Esther Schirrmacher; Klaus Jurkschat; Liuba Iovkova-Berends; Alexey P Kostikov; Ralf Schirrmacher; Björn Wängler
Journal:  Nat Protoc       Date:  2012-10-04       Impact factor: 13.491

9.  Association between cerebral metabolism and Rey-Osterrieth Complex Figure Test performance in Alzheimer's disease.

Authors:  Rebecca J Melrose; Dylan Harwood; Theresa Khoo; Mark Mandelkern; David L Sultzer
Journal:  J Clin Exp Neuropsychol       Date:  2013-02-07       Impact factor: 2.475

10.  Regional distribution of 2-deoxy-2[18F]-fluoro-D-glucose for metabolic imaging using positron emission tomography.

Authors:  P Alagona; D T Hart; E A Eikman
Journal:  Int J Card Imaging       Date:  1994-06
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