Literature DB >> 3711282

Evaluation of a commercial cytotoxicity assay for detection of Clostridium difficile toxin.

I Nachamkin, L Lotz-Nolan, D Skalina.   

Abstract

A comparative study was performed to determine the accuracy of Clostridium difficile toxin detection. A commercial cytotoxicity assay (Bartels Immunodiagnostic Supply, Bellevue, Wash.) was compared with conventional microcytotoxicity assays, using Vero and MRC-5 cells. The Bartels system was found to be essentially equivalent to conventional cytotoxicity assays currently being performed for routine C. difficile toxin detection.

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Year:  1986        PMID： 3711282      PMCID： PMC268758          DOI： 10.1128/jcm.23.5.954-955.1986

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  6 in total

1.  Monoclonal and specific polyclonal antibodies for immunoassay of Clostridium difficile toxin A.

Authors:  D M Lyerly; C J Phelps; T D Wilkins
Journal:  J Clin Microbiol       Date:  1985-01       Impact factor: 5.948

2.  Production of Clostridium difficile antitoxin.

Authors:  M Ehrich; R L Van Tassell; J M Libby; T D Wilkins
Journal:  Infect Immun       Date:  1980-06       Impact factor: 3.441

3.  Colitis induced by Clostridium difficile.

Authors:  J G Bartlett; T Chang; N S Taylor; A B Onderdonk
Journal:  Rev Infect Dis       Date:  1979 Mar-Apr

4.  Relative frequency of Clostridium difficile in patients with diarrheal disease.

Authors:  P H Gilligan; L R McCarthy; V M Genta
Journal:  J Clin Microbiol       Date:  1981-07       Impact factor: 5.948

5.  Enzyme-linked immunosorbent assay for Clostridium difficile toxin A.

Authors:  D M Lyerly; N M Sullivan; T D Wilkins
Journal:  J Clin Microbiol       Date:  1983-01       Impact factor: 5.948

6.  Latex agglutination test for detection of Clostridium difficile toxin in stool samples.

Authors:  M S Shahrabadi; L E Bryan; D Gaffney; S E Coderre; R Gordon; C H Pai
Journal:  J Clin Microbiol       Date:  1984-09       Impact factor: 5.948
  6 in total
  6 in total

Review 1.  Clostridium difficile: its disease and toxins.

Authors:  D M Lyerly; H C Krivan; T D Wilkins
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

2.  Isolation of Clostridium difficile and detection of cytotoxin in the feces of diarrheic foals in the absence of antimicrobial treatment.

Authors:  R L Jones; W S Adney; R K Shideler
Journal:  J Clin Microbiol       Date:  1987-07       Impact factor: 5.948

Review 3.  Clostridium difficile: clinical disease and diagnosis.

Authors:  F C Knoop; M Owens; I C Crocker
Journal:  Clin Microbiol Rev       Date:  1993-07       Impact factor: 26.132

4.  Concurrence of Clostridium difficile toxin A enzyme-linked immunosorbent assay, fecal lactoferrin assay, and clinical criteria with C. difficile cytotoxin titer in two patient cohorts.

Authors:  M A Schleupner; D C Garner; K M Sosnowski; C J Schleupner; L J Barrett; E Silva; D Hirsch; R L Guerrant
Journal:  J Clin Microbiol       Date:  1995-07       Impact factor: 5.948

5.  Laboratory diagnosis of Clostridium difficile-associated gastrointestinal disease: comparison of a monoclonal antibody enzyme immunoassay for toxins A and B with a monoclonal antibody enzyme immunoassay for toxin A only and two cytotoxicity assays.

Authors:  G V Doern; R T Coughlin; L Wu
Journal:  J Clin Microbiol       Date:  1992-08       Impact factor: 5.948

6.  Tolevamer, an anionic polymer, neutralizes toxins produced by the BI/027 strains of Clostridium difficile.

Authors:  Paul L Hinkson; Carol Dinardo; Daniel DeCiero; Jeffrey D Klinger; Robert H Barker
Journal:  Antimicrob Agents Chemother       Date:  2008-04-07       Impact factor: 5.191
  6 in total

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