Literature DB >> 3709645

Effect of terguride on prolactin levels in normal, puerperal and hyperprolactinaemic women.

P L Venturini, R Horowski, M Valenzano, S Costantini, V Fasce, F Gorlero, E Rainer, L De Cecco.   

Abstract

Terguride, is an 8 - alpha - ergoline derived from lisuride, acts as a partial dopamine (DA) agonist. The effect and tolerance of terguride has been investigated by an acute administration of 0.2 mg p.o. to 8 normal women, 8 patients with hyperprolactinaemia and 8 women with puerperal hyperprolactinaemia. Prolactin (PRL) levels were markedly suppressed in all subjects, with no significant differences between the groups. Treatment for 5 days with terguride 0.4 mg/day or 0.8 mg/day was studied as an inhibitor of lactation. PRL levels were suppressed in a dose-related manner. No untoward side-effects were noted.

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Year:  1986        PMID： 3709645     DOI： 10.1007/bf00614302

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  6 in total

1.  Effect of bromocriptine and chlorotrianisene on inhibition of lactation and serum prolactin. A comparative double-blind study.

Authors:  W H Utian; G Begg; A I Vinik; M Paul; L Shuman
Journal:  Br J Obstet Gynaecol       Date:  1975-09

2.  [Inhibition of lactation by N-(D-6-methyl-8-isoergolin-1-yl)-N',N'-diethylurea (VUFB-6638)].

Authors:  M Ausková; K Rezábek; V Zikán; M Semonský
Journal:  Experientia       Date:  1974-04-15

3.  Dual action on central dopamine function of transdihydrolisuride, a 9, 10-dihydrogenated analogue of the ergot dopamine agonist lisuride.

Authors:  H Wachtel; R Dorow
Journal:  Life Sci       Date:  1983-01-24       Impact factor: 5.037

4.  The role of D-1 and D-2 receptors.

Authors:  M Schachter; P Bédard; A G Debono; P Jenner; C D Marsden; P Price; J D Parkes; J Keenan; B Smith; J Rosenthaler; R Horowski; R Dorow
Journal:  Nature       Date:  1980-07-10       Impact factor: 49.962

5.  Effects of lisuride and bromocriptine on inhibition of lactation and on serum prolactin levels: comparative double-blind study.

Authors:  P L Venturini; R Horowski; C Maganza; S Morano; E Pedretti; N Ragni; F Semino; L De Cecco
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  1981-05       Impact factor: 2.435

6.  Effect of lisuride on inhibition of lactation and serum prolactin.

Authors:  L De Cecco; P L Venturini; N Ragni; P Rossato; C Maganza; G Gaggero; R Horowski
Journal:  Br J Obstet Gynaecol       Date:  1979-11
  6 in total
  2 in total

1.  Prolactin and its 16-kDa N-terminal fragment: are higher in patients with precapillary pulmonary hypertension than in a healthy control group.

Authors:  Uta Hönicke; Steffen Albrecht; Hagen Schrötter; Sabine Krug; Martin Kolditz; Eberhard Kuhlisch; Gert Höffken; Michael Halank
Journal:  Tex Heart Inst J       Date:  2012

2.  The effects of additional treatment with terguride, a partial dopamine agonist, on hyperprolactinemia induced by antipsychotics in schizophrenia patients: a preliminary study.

Authors:  Kojiro Hashimoto; Norio Sugawara; Masamichi Ishioka; Kazuhiko Nakamura; Norio Yasui-Furukori
Journal:  Neuropsychiatr Dis Treat       Date:  2014-08-22       Impact factor: 2.570
  2 in total

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