| Literature DB >> 3696192 |
R L Buchanan1, S B Jones, H G Stahl.
Abstract
At 5 microM, miconazole prevented the growth of Aspergillus parasiticus Speare in a number of media. Sensitivity to miconazole was increased approximately 10-fold in a medium containing glycerol. At sub-inhibitory concentrations, miconazole stimulated aflatoxin synthesis on media which normally support toxin formation. Miconazole inhibited respiration and altered mitochondrial ultrastructure, suggesting that miconazole inhibits growth and stimulates aflatoxin production by depressing mitochondrial activity.Entities:
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Year: 1987 PMID： 3696192 DOI： 10.1007/bf00437039
Source DB: PubMed Journal: Mycopathologia ISSN： 0301-486X Impact factor: 2.574