Literature DB >> 3692641

Nifedipine-induced hyporeactivity in delayed hypersensitivity skin tests.

F Derenne1, M Vanhaeverbeek, D Brohée.   

Abstract

Four patients and three healthy volunteers were submitted to delayed hypersensitivity skin tests to candidin, tuberculin, streptokinase/streptodornase (SK/SD) and mumps antigen before and after a 1 week treatment with nifedipine 10 mg q. 8h. A decrease in the scores of induration and erythema was observed, especially in response to SK/SD antigen challenge. We conclude that nifedipine may induce an anergy status in delayed hypersensitivity skin tests.

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Year:  1987        PMID: 3692641     DOI: 10.1016/0192-0561(87)90046-4

Source DB:  PubMed          Journal:  Int J Immunopharmacol        ISSN: 0192-0561


  2 in total

1.  The antiinflammatory activity of topically applied novel calcium-channel antagonists.

Authors:  G W De Vries; A McLaughlin; M B Wenzel; J Perez; D Harcourt; G Lee; M Garst; L A Wheeler
Journal:  Inflammation       Date:  1995-04       Impact factor: 4.092

2.  The Ca2+ Channel Blocker Verapamil Inhibits the In Vitro Activation and Function of T Lymphocytes: A 2022 Reappraisal.

Authors:  José Ignacio Veytia-Bucheli; Den Alejandro Alvarado-Velázquez; Lourival Domingos Possani; Roberto González-Amaro; Yvonne Rosenstein
Journal:  Pharmaceutics       Date:  2022-07-15       Impact factor: 6.525

  2 in total

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