Literature DB >> 3681668

Mean residence time in peripheral tissue.

P J McNamara1, J C Fleishaker, T L Hayden.   

Abstract

The published methods for determining the mean residence time for drugs in peripheral tissue are reviewed in terms of assumptions involved, advantages and disadvantages. A method for determining mean transit time in peripheral tissue is proposed; this may be a more useful indicator of the tissue retention properties for drug compounds.

Mesh：

Year:  1987        PMID： 3681668     DOI： 10.1007/bf01066523

Source DB:  PubMed          Journal:  J Pharmacokinet Biopharm        ISSN： 0090-466X


  17 in total

1.  [Drug distribution in the body. II. Estimation of the concentration of drugs in small anatomic compartments].

Authors:  P P LeBlanc; M LeBel
Journal:  J Pharm Belg       Date:  1986 Mar-Apr

2.  [Drug distribution in the body. I. Estimation of the kinetic rate and quantitation by statistical moments].

Authors:  P P LeBlanc; M LeBel
Journal:  J Pharm Belg       Date:  1986 Mar-Apr

3.  General treatment of linear mammillary models with elimination from any compartment as used in pharmacokinetics.

Authors:  L Z Benet
Journal:  J Pharm Sci       Date:  1972-04       Impact factor: 3.534

4.  Mean residence time in peripheral tissue: a linear disposition parameter useful for evaluating a drug's tissue distribution.

Authors:  P Veng-Pedersen; W Gillespie
Journal:  J Pharmacokinet Biopharm       Date:  1984-10

5.  On some stochastic formulations and related statistical moments of pharmacokinetic models.

Authors:  J H Matis; T E Wehrly; C M Metzler
Journal:  J Pharmacokinet Biopharm       Date:  1983-02

6.  Some considerations on the estimation of steady state apparent volume of distribution and the relationships between volume terms.

Authors:  P S Collier
Journal:  J Pharmacokinet Biopharm       Date:  1983-02

7.  Statistical moments in pharmacokinetics.

Authors:  K Yamaoka; T Nakagawa; T Uno
Journal:  J Pharmacokinet Biopharm       Date:  1978-12

8.  Pharmacokinetics of imipramine and its major metabolites in pregnant rats and their fetuses following a single dose.

Authors:  C L DeVane; J W Simpkins
Journal:  Drug Metab Dispos       Date:  1985 Jul-Aug       Impact factor: 3.922

9.  Physiologically based pharmacokinetic model for beta-lactam antibiotics I: Tissue distribution and elimination in rats.

Authors:  A Tsuji; T Yoshikawa; K Nishide; H Minami; M Kimura; E Nakashima; T Terasaki; E Miyamoto; C H Nightingale; T Yamana
Journal:  J Pharm Sci       Date:  1983-11       Impact factor: 3.534

10.  Performance of a diffusional clearance model for beta-lactam antimicrobial agents as influenced by extravascular protein binding and interstitial fluid kinetics.

Authors:  J C Fleishaker; P J McNamara
Journal:  Antimicrob Agents Chemother       Date:  1985-09       Impact factor: 5.191
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  3 in total

1.  General treatment of mean residence time, clearance, and volume parameters in linear mammillary models with elimination from any compartment.

Authors:  E Nakashima; L Z Benet
Journal:  J Pharmacokinet Biopharm       Date:  1988-10

2.  Dermal and underlying tissue pharmacokinetics of salicylic acid after topical application.

Authors:  P Singh; M S Roberts
Journal:  J Pharmacokinet Biopharm       Date:  1993-08

3.  Determination of cyanidin 3-glucoside in rat brain, liver and kidneys by UPLC/MS-MS and its application to a short-term pharmacokinetic study.

Authors:  Stefano Fornasaro; Lovro Ziberna; Mattia Gasperotti; Federica Tramer; Urška Vrhovšek; Fulvio Mattivi; Sabina Passamonti
Journal:  Sci Rep       Date:  2016-03-11       Impact factor: 4.379
  3 in total

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