Literature DB >> 3679211

Linkage relationship between the genes for adenosine deaminase and S-adenosyl-homocysteine hydrolase on human chromosome 20.

S Bissbort1, H W Hitzeroth, C T van den Berg, T F Wienker.   

Abstract

The genes for adenosine deaminase (ADA) and S-adenosyl homocysteine hydrolase (AHCY or SAHH) are known to be syntenic and within measurable distance from each other, on chromosome 20 in man. In the present study an informative family is described in which the recombination fraction (theta) between the respective genes is estimated to be about 0.18. Together with the published finding of theta = 0.15 (Eiberg and Mohr 1985) in informative Danish families, the recombination fraction for the pooled data is calculated to be theta = 0.14 (in men), theta = 0.08 (in women) and theta = 0.13 (both sexes taken together).

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Year:  1987        PMID： 3679211     DOI： 10.1007/bf00284485

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  8 in total

1.  Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

Authors:  J Ott
Journal:  Am J Hum Genet       Date:  1974-09       Impact factor: 11.025

2.  Assignment of a gene for adenosine deaminase to human chromosome 20.

Authors:  J A Tischfield; R P Creagan; E A Nichols; F H Ruddle
Journal:  Hum Hered       Date:  1974       Impact factor: 0.444

3.  Adenosine deaminase isozymes in human tissues.

Authors:  Y H Edwards; D A Hopkinson; H Harris
Journal:  Ann Hum Genet       Date:  1971-10       Impact factor: 1.670

4.  Investigation of the intrachromosomal position of the ADA locus on chromosome 20 by gene dosage studies.

Authors:  D A Aitken; M A Ferguson-Smith
Journal:  Cytogenet Cell Genet       Date:  1978

5.  Regional assignment of the ADA locus on 20q13.2 leads to qter by gene dosage studies.

Authors:  T Philip; G Lenoir; M O Rolland; I Philip; M Hamet; B Lauras; J Fraisse
Journal:  Cytogenet Cell Genet       Date:  1980

6.  Regional mapping of ADA and ITP on human chromosome 20: cytogenetic and somatic cell studies in an X/20 translocation.

Authors:  T Mohandas; R S Sparkes; M B Passage; M C Sparkes; J H Miles; M M Kaback
Journal:  Cytogenet Cell Genet       Date:  1980

7.  Genetics of human S-adenosylhomocysteine hydrolase. A new polymorphism in man.

Authors:  S Bissbort; K Bender; T F Wienker; K H Grzeschik
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

8.  The human genes for S-adenosylhomocysteine hydrolase and adenosine deaminase are syntenic on chromosome 20.

Authors:  M S Hershfield; U Francke
Journal:  Science       Date:  1982-05-14       Impact factor: 47.728
  8 in total
  4 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Mouse chromosome 2.

Authors:  L D Siracusa; C M Abbott
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 3.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Identification and characterization of nine RFLPs at the adenosine deaminase (ADA) locus.

Authors:  S Tzall; A Ellenbogen; F Eng; R Hirschhorn
Journal:  Am J Hum Genet       Date:  1989-06       Impact factor: 11.025
  4 in total

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