Literature DB >> 367810

Uptake of tolbutamide by islets of Langerhans and other tissues.

H G Joost, S Holze.   

Abstract

3-H-tolbutamide was distributed in a volume exceeding the space occupied by 14-C-sucrose in islets as well as in liver, kidney, muscle, and fat. In contrast to previous reports, the findings suggest that tolbutamide is not restricted to the extracellular space of islets.

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Year:  1978        PMID： 367810     DOI： 10.1007/bf01981481

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  Effects of polymer-linked sulfonylurea derivatives on insulin release.

Authors:  H G Joost; A Hasselblatt
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-03       Impact factor: 3.000

2.  Insulin release from the perfused rat pancreas. Mode of action of tolbutamide.

Authors:  V Bowen; N R Lazarus
Journal:  Biochem J       Date:  1974-08       Impact factor: 3.857

3.  The pancreatic -cell recognition of insulin secretagogues. IV. Islet uptake of sulfonylureas.

Authors:  B Hellman; J Sehlin; I B Täljedal
Journal:  Diabetologia       Date:  1973-06       Impact factor: 10.122

4.  Method for the isolation of intact islets of Langerhans from the rat pancreas.

Authors:  P E Lacy; M Kostianovsky
Journal:  Diabetes       Date:  1967-01       Impact factor: 9.461

5.  The pancreatic -cell recognition of insulin secretagogues. II. Site of action of tolbutamide.

Authors:  B Hellman; J Sehlin; I B Töljedal
Journal:  Biochem Biophys Res Commun       Date:  1971-12-17       Impact factor: 3.575
  5 in total
  1 in total

Review 1.  Interaction of sulfonylurea with the pancreatic B-cell.

Authors:  E Gylfe; B Hellman; J Sehlin; B Täljedal
Journal:  Experientia       Date:  1984-10-15
  1 in total

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