Literature DB >> 3669689

Anti-Bacteroides fragilis substance from rhubarb.

J Cyong1, T Matsumoto, K Arakawa, H Kiyohara, H Yamada, Y Otsuka.   

Abstract

Extracts of 178 Chinese herbs were screened for their antibacterial activity against Bacteroides fragilis a major anaerobic microorganism in the intestinal flora of humans. Only rhubarb root (Rheum officinale) was found to have significant activity and the purified active substance was identified as rhein.

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Year:  1987        PMID： 3669689     DOI： 10.1016/0378-8741(87)90005-5

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  9 in total

1.  Multidrug pump inhibitors uncover remarkable activity of plant antimicrobials.

Authors:  George Tegos; Frank R Stermitz; Olga Lomovskaya; Kim Lewis
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

2.  Can purgation therapy be an adjunct to SDD?

Authors:  X Sun
Journal:  Intensive Care Med       Date:  1992       Impact factor: 17.440

3.  Associations of Gut Microbiota and Fatty Metabolism With Immune Thrombocytopenia.

Authors:  Xiaomin Yu; Qingyun Zheng; Yun He; Dandan Yu; Guolin Chang; Cheng Chen; Laixi Bi; Jia Lv; Misheng Zhao; Xiangyang Lin; Liqing Zhu
Journal:  Front Med (Lausanne)       Date:  2022-05-19

4.  Antioxidant and Anti-Cancer Potentials of Rheum emodi Rhizome Extracts.

Authors:  Venkatadri Rajkumar; Gunjan Guha; Rangasamy Ashok Kumar
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-23       Impact factor: 2.629

5.  Rhein Induces Oxidative Stress and Apoptosis in Mouse Blastocysts and Has Immunotoxic Effects during Embryonic Development.

Authors:  Chien-Hsun Huang; Wen-Hsiung Chan
Journal:  Int J Mol Sci       Date:  2017-09-20       Impact factor: 5.923

Review 6.  Therapeutic Emergence of Rhein as a Potential Anticancer Drug: A Review of Its Molecular Targets and Anticancer Properties.

Authors:  Sahu Henamayee; Kishore Banik; Bethsebie Lalduhsaki Sailo; Bano Shabnam; Choudhary Harsha; Satti Srilakshmi; Naidu Vgm; Seung Ho Baek; Kwang Seok Ahn; Ajaikumar B Kunnumakkara
Journal:  Molecules       Date:  2020-05-12       Impact factor: 4.411

7.  Rhein Elicits In Vitro Cytotoxicity in Primary Human Liver HL-7702 Cells by Inducing Apoptosis through Mitochondria-Mediated Pathway.

Authors:  Guy-Armel Bounda; Wang Zhou; Dan-Dan Wang; Feng Yu
Journal:  Evid Based Complement Alternat Med       Date:  2015-06-14       Impact factor: 2.629

8.  Effects of Rhubarb on Intestinal Dysmotility in Critically Ill Patients.

Authors:  Kentaro Shimizu; Mitsuru Kageyama; Hiroshi Ogura; Tomoki Yamada; Takeshi Shimazu
Journal:  Intern Med       Date:  2017-11-20       Impact factor: 1.271

9.  Preclinical Pharmacokinetics of Scoparone, Geniposide and Rhein in an Herbal Medicine Using a Validated LC-MS/MS Method.

Authors:  Tun-Pin Hsueh; Tung-Hu Tsai
Journal:  Molecules       Date:  2018-10-22       Impact factor: 4.411
  9 in total

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