Literature DB >> 3666283

Ketone bodies inhibit leucine degradation in chick skeletal muscle.

G Wu1, J R Thompson.   

Abstract

1. DL-beta-hydroxybutyrate (4 mM) increased the net rate of leucine transamination and the net rate of 2-oxoisocaproate (KIC) production in extensor digitorum communis muscles from fed chicks. 2. DL-beta-hydroxybutyrate at 1 and 4 mM inhibited leucine oxidative decarboxylation in muscles from fed chicks. 3. Acetoacetate at 1 and 4 mM inhibited leucine oxidative decarboxylation and total leucine oxidation, but increased net KIC production in muscles from fed chicks. 4. Both DL-beta-hydroxybutyrate and acetoacetate at 1 and 4 mM inhibited the net rate of leucine transamination and the rates of leucine oxidative decarboxylation and total leucine oxidation in muscles from 24-hr fasted chicks.

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Year:  1987        PMID: 3666283     DOI: 10.1016/0020-711x(87)90175-3

Source DB:  PubMed          Journal:  Int J Biochem        ISSN: 0020-711X


  7 in total

1.  The effect of ketone bodies on alanine and glutamine metabolism in isolated skeletal muscle from the fasted chick.

Authors:  G Y Wu; J R Thompson
Journal:  Biochem J       Date:  1988-10-01       Impact factor: 3.857

2.  Oral administration of interferon tau enhances oxidation of energy substrates and reduces adiposity in Zucker diabetic fatty rats.

Authors:  Carmen D Tekwe; Jian Lei; Kang Yao; Reza Rezaei; Xilong Li; Sudath Dahanayaka; Raymond J Carroll; Cynthia J Meininger; Fuller W Bazer; Guoyao Wu
Journal:  Biofactors       Date:  2013-06-27       Impact factor: 6.113

3.  Oxidation of amino acids, glucose, and fatty acids as metabolic fuels in enterocytes of developing pigs.

Authors:  Wenliang He; Guoyao Wu
Journal:  Amino Acids       Date:  2022-03-16       Impact factor: 3.520

4.  Oxidation of amino acids, glucose, and fatty acids as metabolic fuels in enterocytes of post-hatching developing chickens.

Authors:  Wenliang He; Kyohei Furukawa; Christopher A Bailey; Guoyao Wu
Journal:  J Anim Sci       Date:  2022-04-01       Impact factor: 3.338

5.  Is methionine transaminated in skeletal muscle?

Authors:  G Y Wu; J R Thompson
Journal:  Biochem J       Date:  1989-01-01       Impact factor: 3.857

6.  The effect of glutamine on protein turnover in chick skeletal muscle in vitro.

Authors:  G Y Wu; J R Thompson
Journal:  Biochem J       Date:  1990-01-15       Impact factor: 3.857

7.  Interorgan Metabolism, Nutritional Impacts, and Safety of Dietary L-Glutamate and L-Glutamine in Poultry.

Authors:  Wenliang He; Kyohei Furukawa; Masaaki Toyomizu; Tomonori Nochi; Christopher A Bailey; Guoyao Wu
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

  7 in total

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