The relationship of retinal sensitivity and rhodopsin in human infants.

During dark adaptation after full field, greater than or equal to 90% bleaches recovery of sensitivity and regeneration of rhodopsin were studied using electroretinographic and pupillographic techniques in both 10-week-old infants and adults. The courses of scotopic sensitivity recovery and rhodopsin regeneration of infants and adults were similar and were reasonably well fit by single exponentials having tau = 400 sec. For both infants and adults log scotopic sensitivity was linearly related to the proportion of rhodopsin present during dark adaptation. It is concluded that by age 10 weeks human distal retinal processes that occur after photolysis are equivalent to those of adults.