Literature DB >> 3654015

Comparative anti-fertility effects of gossypol enantiomers in male hamsters.

M C Lindberg1, R H Naqvi, S A Matlin, R H Zhou, G Bialy, R P Blye.   

Abstract

The enantiomers of gossypol have been tested as male oral anti-fertility agents in hamsters. As determined by fertility tests the (-) isomer was fully active at half the effective dose of the racemate, whereas the (+) isomer exerted no anti-fertility effect.

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Year:  1987        PMID： 3654015     DOI： 10.1111/j.1365-2605.1987.tb00361.x

Source DB:  PubMed          Journal:  Int J Androl        ISSN： 0105-6263


  4 in total

Review 1.  An overview of the clinical pharmacology and therapeutic potential of gossypol as a male contraceptive agent and in gynaecological disease.

Authors:  D Wu
Journal:  Drugs       Date:  1989-09       Impact factor: 9.546

2.  Gene expression profiling during gland morphogenesis of a mutant and a glandless upland cotton.

Authors:  Quan Sun; Yingfan Cai; Yongfang Xie; Jianchuan Mo; Youlu Yuan; Yuzhen Shi; Shengwei Li; Huaizhong Jiang; Zheng Pan; Yunling Gao; Min Chen; Xiaohong He
Journal:  Mol Biol Rep       Date:  2009-11-04       Impact factor: 2.316

Review 3.  Prospects for pharmacological male contraception.

Authors:  S A Matlin
Journal:  Drugs       Date:  1994-12       Impact factor: 9.546

4.  Effect of racemic and (+)- and (-)-gossypol on the survival and development of Helicoverpa zea larvae.

Authors:  Robert D Stipanovic; Juan D Lopez; Michael K Dowd; Lorraine S Puckhaber; Sara E Duke
Journal:  J Chem Ecol       Date:  2006-05-19       Impact factor: 2.626
  4 in total

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