Literature DB >> 3653889

A comparative mapping study of fragile sites in the human and murine genomes.

M Djalali1, S Adolph, P Steinbach, H Winking, H Hameister.   

Abstract

Fragile sites on murine chromosomes were induced by the antimetabolites methotrexate (MTX), fluorodeoxyuridine (FdU), and aphidicolin (APD). To facilitate chromosome identification the analysis was performed on chromosomes of a CD/CD mouse that possesses nine pairs of Robertsonian translocation chromosomes of known arm composition. The pattern of induced fragile sites was rather similar for the different antimetabolites used. Many of them, e.g., 2B, 3B, 5B and 9D, are included in Giemsa-negative bands. On the X chromosome a fragile site was mapped to the region XC/D. Comparative mapping data with human fragile sites have been informative in most instances. Conservation of synteny within known linkage groups seems very likely.

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Year:  1987        PMID： 3653889     DOI： 10.1007/BF00272384

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  25 in total

1.  Report of the Committee on Chromosome Rearrangements in Neoplasia and on Fragile Sites.

Authors:  R Berger; C D Bloomfield; G R Sutherland
Journal:  Cytogenet Cell Genet       Date:  1985

Review 2.  Fragile X syndrome: a unique mutation in man.

Authors:  R L Nussbaum; D H Ledbetter
Journal:  Annu Rev Genet       Date:  1986       Impact factor: 16.830

3.  Replication timing of genes and middle repetitive sequences.

Authors:  M A Goldman; G P Holmquist; M C Gray; L A Caston; A Nag
Journal:  Science       Date:  1984-05-18       Impact factor: 47.728

4.  Conference report: International Workshop on the fragile X and X-linked mental retardation.

Authors:  J M Opitz; G R Sutherland
Journal:  Am J Med Genet       Date:  1984-01

5.  Lengths of chromosomal segments conserved since divergence of man and mouse.

Authors:  J H Nadeau; B A Taylor
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

6.  Chromosome maps of man and mouse II.

Authors:  V J Buckle; J H Edwards; E P Evans; J A Jonasson; M F Lyon; J Peters; A G Searle; N S Wedd
Journal:  Clin Genet       Date:  1984-07       Impact factor: 4.438

7.  DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes.

Authors:  T W Glover; C Berger; J Coyle; B Echo
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

8.  Genetic mapping in mammals: chromosome map of domestic cat.

Authors:  S J O'Brien; W G Nash
Journal:  Science       Date:  1982-04-16       Impact factor: 47.728

9.  An in vitro and in vivo study of a BrdU-sensitive fragile site in the Chinese hamster.

Authors:  M S Lin; T Takabayashi; M G Wilson; C A Marchese
Journal:  Cytogenet Cell Genet       Date:  1984

10.  Constitutive fragile sites and cancer.

Authors:  J J Yunis; A L Soreng
Journal:  Science       Date:  1984-12-07       Impact factor: 47.728
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  11 in total

1.  Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability.

Authors:  A Hellman; A Rahat; S W Scherer; A Darvasi; L C Tsui; B Kerem
Journal:  Mol Cell Biol       Date:  2000-06       Impact factor: 4.272

2.  Aphidicolin-inducible common fragile-site expression: results from a population survey of twins.

Authors:  M J Austin; J M Collins; L A Corey; W E Nance; M C Neale; R M Schieken; J A Brown
Journal:  Am J Hum Genet       Date:  1992-01       Impact factor: 11.025

3.  Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit.

Authors:  T Shiraishi; T Druck; K Mimori; J Flomenberg; L Berk; H Alder; W Miller; K Huebner; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-24       Impact factor: 11.205

4.  Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites.

Authors:  F V Rassool; T W McKeithan; M E Neilly; E van Melle; R Espinosa; M M Le Beau
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-01       Impact factor: 11.205

5.  Rodent common fragile sites: are they conserved? Evidence from mouse and rat.

Authors:  F F Elder; T J Robinson
Journal:  Chromosoma       Date:  1989-05       Impact factor: 4.316

6.  Fragile sites in human and Macaca fascicularis chromosomes are breakpoints in chromosome evolution.

Authors:  A Ruiz-Herrera; M Ponsà; F García; J Egozcue; M García
Journal:  Chromosome Res       Date:  2002       Impact factor: 5.239

7.  Common chromosome fragile sites in human and murine epithelial cells and FHIT/FRA3B loss-induced global genome instability.

Authors:  Seyed Ali Hosseini; Susan Horton; Joshua C Saldivar; Satoshi Miuma; Martha R Stampfer; Nyla A Heerema; Kay Huebner
Journal:  Genes Chromosomes Cancer       Date:  2013-08-09       Impact factor: 5.006

8.  Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution.

Authors:  Claus Kemkemer; Matthias Kohn; David N Cooper; Lutz Froenicke; Josef Högel; Horst Hameister; Hildegard Kehrer-Sawatzki
Journal:  BMC Evol Biol       Date:  2009-04-24       Impact factor: 3.260

9.  Initiation of genome instability and preneoplastic processes through loss of Fhit expression.

Authors:  Joshua C Saldivar; Satoshi Miuma; Jessica Bene; Seyed Ali Hosseini; Hidetaka Shibata; Jin Sun; Linda J Wheeler; Christopher K Mathews; Kay Huebner
Journal:  PLoS Genet       Date:  2012-11-29       Impact factor: 5.917

10.  Fhit deficiency-induced global genome instability promotes mutation and clonal expansion.

Authors:  Satoshi Miuma; Joshua C Saldivar; Jenna R Karras; Catherine E Waters; Carolyn A Paisie; Yao Wang; Victor Jin; Jin Sun; Teresa Druck; Jie Zhang; Kay Huebner
Journal:  PLoS One       Date:  2013-11-14       Impact factor: 3.240
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