Yunqing Zhu1, Junning Fan1, Jun Lv1,2, Yu Guo3, Pei Pei4, Ling Yang5,6, Yiping Chen5,6, Huaidong Du5,6, Feifei Li7, Xiaoming Yang6, Daniel Avery6, Junshi Chen8, Zhengming Chen6, Canqing Yu9,10, Liming Li1,2. 1. Department of Epidemiology & Biostatistics, School of Public Health, Peking University, 100191, Beijing, China. 2. Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, 100191, China. 3. Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, 100037, China. 4. Chinese Academy of Medical Sciences, Beijing, 100730, China. 5. Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, OX3 7LF, UK. 6. Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK. 7. NCDs Prevention and Control Department, Qingdao CDC, Qingdao, 266033, Shandong, China. 8. China National Center for Food Safety Risk Assessment, Beijing, 100022, China. 9. Department of Epidemiology & Biostatistics, School of Public Health, Peking University, 100191, Beijing, China. yucanqing@pku.edu.cn. 10. Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, 100191, China. yucanqing@pku.edu.cn.
Abstract
BACKGROUND: Little is known about the effects of maintaining healthy sleep patterns on frailty transitions. METHODS: Based on 23,847 Chinese adults aged 30-79 in a prospective cohort study, we examined the associations between sleep patterns and frailty transitions. Healthy sleep patterns included sleep duration at 7 or 8 h/d, without insomnia disorder, and no snoring. Participants who persisted with a healthy sleep pattern in both surveys were defined as maintaining a healthy sleep pattern and scored one point. We used 27 phenotypes to construct a frailty index and defined three statuses: robust, prefrail, and frail. Frailty transitions were defined as the change of frailty status between the 2 surveys: improved, worsened, and remained. Log-binomial regression was used to calculate the prevalence ratio (PR) to assess the effect of sleep patterns on frailty transitions. RESULTS: During a median follow-up of 8.0 years among 23,847 adults, 45.5% of robust participants, and 10.8% of prefrail participants worsened their frailty status, while 18.6% of prefrail participants improved. Among robust participants at baseline, individuals who maintained sleep duration of 7 or 8 h/ds, without insomnia disorder, and no-snoring were less likely to worsen their frailty status; the corresponding PRs (95% CIs) were 0.92 (0.89-0.96), 0.76 (0.74-0.77), and 0.85 (0.82-0.88), respectively. Similar results were observed among prefrail participants maintaining healthy sleep patterns. Maintaining healthy sleep duration and without snoring, also raised the probability of improving the frailty status; the corresponding PRs were 1.09 (1.00-1.18) and 1.42 (1.31-1.54), respectively. Besides, a dose-response relationship was observed between constantly healthy sleep scores and the risk of frailty transitions (P for trend < 0.001). CONCLUSIONS: Maintaining a comprehensive healthy sleep pattern was positively associated with a lower risk of worsening frailty status and a higher probability of improving frailty status among Chinese adults.
BACKGROUND: Little is known about the effects of maintaining healthy sleep patterns on frailty transitions. METHODS: Based on 23,847 Chinese adults aged 30-79 in a prospective cohort study, we examined the associations between sleep patterns and frailty transitions. Healthy sleep patterns included sleep duration at 7 or 8 h/d, without insomnia disorder, and no snoring. Participants who persisted with a healthy sleep pattern in both surveys were defined as maintaining a healthy sleep pattern and scored one point. We used 27 phenotypes to construct a frailty index and defined three statuses: robust, prefrail, and frail. Frailty transitions were defined as the change of frailty status between the 2 surveys: improved, worsened, and remained. Log-binomial regression was used to calculate the prevalence ratio (PR) to assess the effect of sleep patterns on frailty transitions. RESULTS: During a median follow-up of 8.0 years among 23,847 adults, 45.5% of robust participants, and 10.8% of prefrail participants worsened their frailty status, while 18.6% of prefrail participants improved. Among robust participants at baseline, individuals who maintained sleep duration of 7 or 8 h/ds, without insomnia disorder, and no-snoring were less likely to worsen their frailty status; the corresponding PRs (95% CIs) were 0.92 (0.89-0.96), 0.76 (0.74-0.77), and 0.85 (0.82-0.88), respectively. Similar results were observed among prefrail participants maintaining healthy sleep patterns. Maintaining healthy sleep duration and without snoring, also raised the probability of improving the frailty status; the corresponding PRs were 1.09 (1.00-1.18) and 1.42 (1.31-1.54), respectively. Besides, a dose-response relationship was observed between constantly healthy sleep scores and the risk of frailty transitions (P for trend < 0.001). CONCLUSIONS: Maintaining a comprehensive healthy sleep pattern was positively associated with a lower risk of worsening frailty status and a higher probability of improving frailty status among Chinese adults.
Authors: Jin-Gun Cho; Paul K Witting; Manisha Verma; Ben J Wu; Anu Shanu; Kristina Kairaitis; Terence C Amis; John R Wheatley Journal: Sleep Date: 2011-06-01 Impact factor: 5.849
Authors: Max Hirshkowitz; Kaitlyn Whiton; Steven M Albert; Cathy Alessi; Oliviero Bruni; Lydia DonCarlos; Nancy Hazen; John Herman; Eliot S Katz; Leila Kheirandish-Gozal; David N Neubauer; Anne E O'Donnell; Maurice Ohayon; John Peever; Robert Rawding; Ramesh C Sachdeva; Belinda Setters; Michael V Vitiello; J Catesby Ware; Paula J Adams Hillard Journal: Sleep Health Date: 2015-01-08
Authors: AnnaLynn M Williams; Kevin R Krull; Carrie R Howell; Pia Banerjee; Tara M Brinkman; Sue C Kaste; Robyn E Partin; Deokumar Srivastava; Yutaka Yasui; Gregory T Armstrong; Leslie L Robison; Melissa M Hudson; Kirsten K Ness Journal: J Clin Oncol Date: 2021-07-20 Impact factor: 44.544