Literature DB >> 36263333

How does spinopelvic alignment influence short-term clinical outcomes after lumbar fusion in patients with single-level degenerative spondylolisthesis?

Stephen DiMaria1, Brian A Karamian1, Mark J Lambrechts1, Arun P Kanhere1, John J Mangan1, Winston W Yen2, Arlene Maheu1, Mahir A Qureshi1, Jose A Canseco1, David I Kaye1, Barrett I Woods1, Mark F Kurd1, Kris E Radcliff1, Alan S Hilibrand1, Christopher K Kepler1, Alexander R Vaccaro1, Gregory D Schroeder1.   

Abstract

Context: Studies on adult spinal deformity have shown spinopelvic malalignment results in worse outcomes. However, it is unclear if this relationship exists in patients with single-level degenerative spondylolisthesis (DS) receiving short-segment fusions. Aims: To determine if spinopelvic alignment affects patient-reported outcome measures (PROMs) after posterior lumbar decompression and fusion (PLDF) with or without a transforaminal lumbar interbody fusion in patients with L4-5 DS. Settings and Design: A retrospective cohort analysis was conducted on patients who underwent PLDF for L4-5 DS at a single tertiary referral academic medical center. Materials and
Methods: Patients were divided into groups based on preoperative cutoff values of 20° for pelvic tilt (PT) and 11° for pelvic incidence-lumbar lordosis mismatch (PI-LL) with subsequent reclassification based on correction to <20° PT or 11° PI-LL. Radiographic outcomes and PROMs were compared between the groups. Statistical Analysis Used: Multiple linear regression analyses were performed to determine whether radiographic cutoff values served as the independent predictors of change in PROMs. Statistical significance was set at P < 0.05.
Results: A total of 188 patients with completed PROMs were included for the analysis. Preoperative PT >20° was associated with significantly greater reduction in PI-LL (-2.41° vs. 1.21°, P = 0.004) and increase in sacral slope (SS) (1.06° vs. -1.86°, P = 0.005) compared to patients with preoperative PT <20°. On univariate analysis, no significant differences were observed between any groups with regard to PROMs. Preoperative sagittal alignment measures and postoperative correction were not found to be independent predictors of improvement in clinical outcomes.
Conclusion: A preoperative PT >20° is associated with improved PI-LL reduction and an increase in SS. However, no differences in clinical outcomes were found 1 year postoperatively for patients with preoperative PT >20° and PI-LL ≥11° compared to patients below this threshold. Copyright:
© 2022 Journal of Craniovertebral Junction and Spine.

Entities:  

Keywords:  Degenerative spondylolisthesis; lumbar lordosis; patient-reported outcome measures; pelvic tilt; sacral slope; spinopelvic alignment

Year:  2022        PMID: 36263333      PMCID: PMC9574120          DOI: 10.4103/jcvjs.jcvjs_58_22

Source DB:  PubMed          Journal:  J Craniovertebr Junction Spine        ISSN: 0974-8237


  37 in total

Review 1.  Implications of spinopelvic alignment for the spine surgeon.

Authors:  Vivek A Mehta; Anubhav Amin; Ibrahim Omeis; Ziya L Gokaslan; Oren N Gottfried
Journal:  Neurosurgery       Date:  2012-03       Impact factor: 4.654

2.  Comparative study of spinopelvic sagittal alignment between patients with and without degenerative spondylolisthesis.

Authors:  Haruki Funao; Takashi Tsuji; Naobumi Hosogane; Kota Watanabe; Ken Ishii; Masaya Nakamura; Kazuhiro Chiba; Yoshiaki Toyama; Morio Matsumoto
Journal:  Eur Spine J       Date:  2012-05-26       Impact factor: 3.134

3.  1997 Volvo Award winner in clinical studies. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation.

Authors:  J S Fischgrund; M Mackay; H N Herkowitz; R Brower; D M Montgomery; L T Kurz
Journal:  Spine (Phila Pa 1976)       Date:  1997-12-15       Impact factor: 3.468

4.  Spinopelvic alignment of patients with degenerative spondylolisthesis.

Authors:  Cédric Barrey; Jérôme Jund; Gilles Perrin; Pierre Roussouly
Journal:  Neurosurgery       Date:  2007-11       Impact factor: 4.654

5.  Pelvic tilt and truncal inclination: two key radiographic parameters in the setting of adults with spinal deformity.

Authors:  Virginie Lafage; Frank Schwab; Ashish Patel; Nicola Hawkinson; Jean-Pierre Farcy
Journal:  Spine (Phila Pa 1976)       Date:  2009-08-01       Impact factor: 3.468

6.  Surgical compared with nonoperative treatment for lumbar degenerative spondylolisthesis. four-year results in the Spine Patient Outcomes Research Trial (SPORT) randomized and observational cohorts.

Authors:  James N Weinstein; Jon D Lurie; Tor D Tosteson; Wenyan Zhao; Emily A Blood; Anna N A Tosteson; Nancy Birkmeyer; Harry Herkowitz; Michael Longley; Lawrence Lenke; Sanford Emery; Serena S Hu
Journal:  J Bone Joint Surg Am       Date:  2009-06       Impact factor: 5.284

7.  The relationship between spinopelvic parameters and clinical symptoms of severe isthmic spondylolisthesis: a prospective study of 64 patients.

Authors:  Zhengguang Wang; Bing Wang; Bangliang Yin; Weidong Liu; Fan Yang; Guohua Lv
Journal:  Eur Spine J       Date:  2013-10-20       Impact factor: 3.134

8.  Clinical and radiographic degenerative spondylolisthesis (CARDS) classification.

Authors:  Christopher K Kepler; Alan S Hilibrand; Amir Sayadipour; John D Koerner; Jeffrey A Rihn; Kristen E Radcliff; Alexander R Vaccaro; Todd J Albert; D Greg Anderson
Journal:  Spine J       Date:  2014-04-03       Impact factor: 4.166

9.  The impact of sagittal balance on clinical results after posterior interbody fusion for patients with degenerative spondylolisthesis: a pilot study.

Authors:  Mi Kyung Kim; Sun-Ho Lee; Eun-Sang Kim; Whan Eoh; Sung-Soo Chung; Chong-Suh Lee
Journal:  BMC Musculoskelet Disord       Date:  2011-04-05       Impact factor: 2.362

Review 10.  Degenerative lumbar spondylolisthesis: cohort of 670 patients, and proposal of a new classification.

Authors:  O Gille; V Challier; H Parent; R Cavagna; A Poignard; A Faline; S Fuentes; O Ricart; E Ferrero; M Ould Slimane
Journal:  Orthop Traumatol Surg Res       Date:  2014-09-05       Impact factor: 2.256

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