Literature DB >> 36262890

Chemotherapy Port Induced SVC Thrombosis in a Patient with Non-metastatic Breast Cancer.

Brooke Kania1, Erinie Mekheal1, Moutaz Ghrewati2, Nader Mekheal1, Jalal Koj1, Alisa Farokhian1, Michael Maroules1,2.   

Abstract

Cancer patients are at a higher risk of complications such as venous thromboembolism (VTE). This risk increases in patients who receive chemotherapy. Despite the increased risk, common locations for VTE are similar to those in patients without cancer. Chemotherapy-port-related thrombosis represents a rare complication due to the location and frequent use of access (with Heparin flushes) as part of the standard care. Attention should be made to this rare complication, which may progress to superior vena cava (SVC) syndrome. SVC syndrome typically presents in females around the age of 57 years old. Management of this syndrome can be difficult and generally requires the initiation of systemic anticoagulation therapy. Here, we present a rare case of a 45-year-old female who presented to the Emergency Department with right arm swelling, found to be secondary to her chemo port thrombosis, causing SVC syndrome.
© 2022 Greater Baltimore Medical Center.

Entities:  

Keywords:  Breast cancer; Port thrombosis; SVC syndrome

Year:  2022        PMID: 36262890      PMCID: PMC9533793          DOI: 10.55729/2000-9666.1077

Source DB:  PubMed          Journal:  J Community Hosp Intern Med Perspect        ISSN: 2000-9666


  17 in total

Review 1.  International clinical practice guidelines for the treatment and prophylaxis of thrombosis associated with central venous catheters in patients with cancer.

Authors:  P Debourdeau; D Farge; M Beckers; C Baglin; R M Bauersachs; B Brenner; D Brilhante; A Falanga; G T Gerotzafias; N Haim; A K Kakkar; A A Khorana; R Lecumberri; M Mandala; M Marty; M Monreal; S A Mousa; S Noble; I Pabinger; P Prandoni; M H Prins; M H Qari; M B Streiff; K Syrigos; H R Büller; H Bounameaux
Journal:  J Thromb Haemost       Date:  2013-01       Impact factor: 5.824

Review 2.  Thrombolytic therapy for central venous catheter occlusion.

Authors:  Jacquelyn L Baskin; Ulrike Reiss; Judith A Wilimas; Monika L Metzger; Raul C Ribeiro; Ching-Hon Pui; Scott C Howard
Journal:  Haematologica       Date:  2011-12-16       Impact factor: 9.941

3.  Incidence of central vein stenosis and occlusion following upper extremity PICC and port placement.

Authors:  Carin F Gonsalves; David J Eschelman; Kevin L Sullivan; Nancy DuBois; Joseph Bonn
Journal:  Cardiovasc Intervent Radiol       Date:  2003-03-06       Impact factor: 2.740

4.  Ultrasound screening for internal jugular vein thrombosis aids the detection of central venous catheter-related infections in patients with haemato-oncological diseases: a prospective observational study.

Authors:  Florian Lordick; Markus Hentrich; Thomas Decker; Michael Hennig; Hans Pohlmann; Reiner Hartenstein; Christian Peschel
Journal:  Br J Haematol       Date:  2003-03       Impact factor: 6.998

5.  Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Authors:  Clive Kearon; Susan R Kahn; Giancarlo Agnelli; Samuel Goldhaber; Gary E Raskob; Anthony J Comerota
Journal:  Chest       Date:  2008-06       Impact factor: 9.410

6.  Superior vena cava thrombosis related to catheter malposition in cancer chemotherapy given through implanted ports.

Authors:  V Puel; M Caudry; P Le Métayer; J C Baste; D Midy; C Marsault; H Demeaux; J P Maire
Journal:  Cancer       Date:  1993-10-01       Impact factor: 6.860

7.  The superior vena cava syndrome: clinical characteristics and evolving etiology.

Authors:  Todd W Rice; R Michael Rodriguez; Richard W Light
Journal:  Medicine (Baltimore)       Date:  2006-01       Impact factor: 1.889

8.  Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update.

Authors:  Nigel S Key; Alok A Khorana; Nicole M Kuderer; Kari Bohlke; Agnes Y Y Lee; Juan I Arcelus; Sandra L Wong; Edward P Balaban; Christopher R Flowers; Charles W Francis; Leigh E Gates; Ajay K Kakkar; Mark N Levine; Howard A Liebman; Margaret A Tempero; Gary H Lyman; Anna Falanga
Journal:  J Clin Oncol       Date:  2019-08-05       Impact factor: 44.544

9.  Vitamin K Antagonists Compared to Low-Molecular-Weight Heparins for Treatment of Cancer-Associated Venous Thromboembolism: An Observational Study in Routine Clinical Practice. An Observational Study in Routine Clinical Practice.

Authors:  Paul L den Exter; José Hooijer; Tom van der Hulle; Julien P van Oosten; Olaf M Dekkers; Frederikus A Klok; Menno V Huisman
Journal:  Thromb Haemost       Date:  2017-10-04       Impact factor: 5.249

10.  Venous thromboembolism in cancer patients: report of baseline data from the multicentre, prospective Cancer-VTE Registry.

Authors:  Yasuo Ohashi; Masataka Ikeda; Hideo Kunitoh; Mitsuru Sasako; Takuji Okusaka; Hirofumi Mukai; Keiichi Fujiwara; Mashio Nakamura; Mari S Oba; Tetsuya Kimura; Kei Ibusuki; Masato Sakon
Journal:  Jpn J Clin Oncol       Date:  2020-10-22       Impact factor: 3.019

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