| Literature DB >> 36261431 |
Shizhe Yu1,2, Haoren Wang1, Lingpeng Yang2, Yingxue Yan1, Qiang Cai2, Duo Ma2, Long Jiang2, Zehai Gao2, Zhiyong Yu3, Zongping Xia4.
Abstract
The comprehensive study of the spatial-cellular anatomy of the human liver is critical to addressing the cellular origins of liver disease. Here we conducted spatial transcriptomics on normal human liver tissue sections, providing detailed information of liver zonation at the transcriptional level. We present 6581 high-quality spots from normal livers of two human donors. In this dataset, cells were mainly hepatocytes, and we classified them into four sub-groups. Collectively, these data provide a reliable reference for studies on spatial heterogeneity of liver lobules.Entities:
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Year: 2022 PMID： 36261431 PMCID： PMC9581974 DOI： 10.1038/s41597-022-01676-w
Source DB: PubMed Journal: Sci Data ISSN： 2052-4463 Impact factor: 8.501