Literature DB >> 36258934

Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report of a Rare Type of Invasive Carcinoma.

Sara Salehiazar1, Hehua Huang1, Maryam Aghighi2, Rose Venegas1.   

Abstract

Lymphoepithelioma carcinoma (LELC) is an extremely rare type of mammary cancer. Based on the histology, it can be misdiagnosed with inflammatory lesions like mastitis and medullary carcinoma or other hematopoietic neoplasms like lymphoma in the breast. Since LELC has a good response to chemotherapy with a good prognosis, t is prognostically important to recognize LELC. We report a rare case of LELC in a 51-year-old pre-menopausal female with a left breast mass, diagnosed with invasive ductal carcinoma (IDC), LELC type, treated with mastectomy, followed by adjuvant chemotherapy and radiotherapy, with a disease-free interval of 10 months. Herein, we present the case with its clinical presentation, radiologic imaging, histopathological features, and immunohistochemistry (IHC) findings. The rarity of this type of breast tumor warrants studying the behavior of these uncommon tumors to avoid misdiagnosis and establish well-defined criteria for diagnosis.
Copyright © 2022, Salehiazar et al.

Entities:  

Keywords:  breast invasive carcinoma; good prognosis; lymphoepithelioma-like carcinoma; medullary lymphoma carcinoma; triple-negative breast carcinoma

Year:  2022        PMID: 36258934      PMCID: PMC9573688          DOI: 10.7759/cureus.29231

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  12 in total

1.  Lymphoepithelioma-like carcinoma of the breast: a diagnostic and therapeutic challenge.

Authors:  R Dinniwell; W M Hanna; M Mashhour; R S Saad; G J Czarnota
Journal:  Curr Oncol       Date:  2012-06       Impact factor: 3.677

2.  Lymphoepithelioma-like carcinoma of the breast.

Authors:  S Kumar; D Kumar
Journal:  Mod Pathol       Date:  1994-01       Impact factor: 7.842

3.  Lymphoepithelioma-like carcinoma of the breast: report of a case mimicking lymphoma.

Authors:  Souzan Sanati; Alberto G Ayala; Lavinia P Middleton
Journal:  Ann Diagn Pathol       Date:  2004-10       Impact factor: 2.090

4.  Lymphoepithelioma-like carcinoma of the breast presenting as breast abscess.

Authors:  Ikumi Suzuki; Pimchandr Chakkabat; Lindsay Goicochea; Cristina Campassi; Saranya Chumsri
Journal:  World J Clin Oncol       Date:  2014-12-10

Review 5.  Lymphoepithelioma-like carcinoma of breast: A case report and review of the literature.

Authors:  María Tereza Nieto-Coronel; Víctor Manuel Perez-Sanchez; Jessica Elizabeth Salazar-Campos; Raul Diaz-Molina; Claudia Haydee Arce-Salinas
Journal:  Indian J Pathol Microbiol       Date:  2019 Jan-Mar       Impact factor: 0.740

6.  Lymphoepithelioma-like carcinoma of the breast: not Epstein-Barr virus-, but human papilloma virus-positive.

Authors:  Janina Kulka; Ilona Kovalszky; Egon Svastics; Mária Berta; Tibor Füle
Journal:  Hum Pathol       Date:  2008-02       Impact factor: 3.466

7.  KIT (CD117)-positive breast cancers are infrequent and lack KIT gene mutations.

Authors:  Ronald Simon; Soti Panussis; Robert Maurer; Hanspeter Spichtin; Kathrin Glatz; Coya Tapia; Martina Mirlacher; Alex Rufle; Joachim Torhorst; Guido Sauter
Journal:  Clin Cancer Res       Date:  2004-01-01       Impact factor: 12.531

8.  Lymphoepithelioma-Like Carcinoma of the Breast Mimicking Granulomatous Mastitis- Case Report and Review of the Literature

Authors:  Dalia M Abouelfad; Noha N Yassen; Hebat Allah A Amin; Marwa E Shabana
Journal:  Asian Pac J Cancer Prev       Date:  2017-07-27

9.  Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges.

Authors:  Tarek Aridi; Mohamad Fawwaz; Ahmad Kassab; Marwan Bahmad; Faisal Houcheimi; Mohamad Mshiek; Fouad Boulos; Ali Kanj; Ghassan Ramadan; Hisham F Bahmad; Najla Fakhruddin
Journal:  Case Rep Surg       Date:  2018-07-12

Review 10.  Lymphoepithelioma-like carcinoma of the breast: a case report and review of the literature.

Authors:  Kouhen Fadila; Abbad Faycal; Jabri Lamiaa; Belghiti Mohammed; Ismaili Nabil
Journal:  Pan Afr Med J       Date:  2019-01-11
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