Giovanni Defazio1, Mark Hallett2, Alfredo Berardelli3,4, Joel S Perlmutter5, Brian D Berman6, Joseph Jankovic7, Tobias Bäumer8, Cynthia Comella9, Tommaso Ercoli1, Gina Ferrazzano3, Susan H Fox10, Han-Joon Kim11, Emile Sami Moukheiber12, Sarah Pirio Richardson13, Anne Weissbach7,14, Angelo F Gigante15, Hyder A Jinnah16. 1. Department of Medical Sciences and Public Health University of Cagliari Cagliari Italy. 2. Human Motor Control Section, NINDS, NIH Bethesda MD USA. 3. Department of Human Neurosciences Sapienza University of Rome Rome Italy. 4. IRCCS NEUROMED Pozzilli Italy. 5. Neurology, Radiology, Neuroscience, Physical Therapy, Occupational Therapy Washington University in St. Louis St Louis MO USA. 6. Virginia Commonwealth University Richmond VA USA. 7. Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology Baylor College of Medicine Houston TX USA. 8. Institute of Systems Motor Science University of Luebeck Luebeck Germany. 9. Rush University Medical Center New Philadelphia OH USA. 10. Toronto Western Hospital, Krembil Brain Institute University of Toronto Toronto ON Canada. 11. Department of Neurology and Movement Disorder Centre Seoul National University Hospital Seoul South Korea. 12. Department of Neurology Johns Hopkins University Baltimore MD USA. 13. Department of Neurology University of New Mexico Albuquerque NM USA. 14. Institute of Systems Motor Science and Institute of Neurogenetics University of Lübeck , Lübeck Germany. 15. Section of Neurology San Paolo Hospital Bari Italy. 16. Department of Neurology and Human Genetics Emory University Atlanta GA USA.
Abstract
Background: Several scales have been proposed to clinically evaluate the Motor Severity of Blepharospasm (BSP) but information about their measurement properties as a multicenter instrument is limited. Objective: To compare the measurement properties of four clinical scales in rating the severity of BSP in a large sample of patients from multiple sites. Methods: The Burke-Fahn-Marsden Scale (BFMS), the Global Dystonia Severity Rating Scale (GDRS), the Jankovic Rating Scale (JRS), and the Blepharospasm Severity Rating Scale (BSRS) were administered to 211 patients across 10 sites who were also requested to self-complete the Blepharospasm Disability Index (BDI). Measurement properties to be assessed included inter-/intra-observer agreement, item-to-total correlation, internal consistency, floor and ceiling effect, convergent/discriminant validity, and adherence to the distribution of BDI. Results: The BFMS had unsatisfactory measurement properties, the GDRS had acceptable reliability but other properties could not be completely testable; the JRS had satisfactory measurement properties but the scale did not accurately reflect the distribution of disability parameter (BDI) in the sample, and the BSRS had satisfactory measurement properties and also showed the best adherence to the distribution of BDI in the assessed sample. Conclusion: The comparison of the measurement properties of four rating scales to assess the motor state of the BSP in a large sample of patients from multiple sites showed that the GDRS should be used to simultaneously assess BSP and dystonia in other body parts, while the JRS (easier to use) and BSRS (better to discriminate severity) should be used to assess BSP alone.
Background: Several scales have been proposed to clinically evaluate the Motor Severity of Blepharospasm (BSP) but information about their measurement properties as a multicenter instrument is limited. Objective: To compare the measurement properties of four clinical scales in rating the severity of BSP in a large sample of patients from multiple sites. Methods: The Burke-Fahn-Marsden Scale (BFMS), the Global Dystonia Severity Rating Scale (GDRS), the Jankovic Rating Scale (JRS), and the Blepharospasm Severity Rating Scale (BSRS) were administered to 211 patients across 10 sites who were also requested to self-complete the Blepharospasm Disability Index (BDI). Measurement properties to be assessed included inter-/intra-observer agreement, item-to-total correlation, internal consistency, floor and ceiling effect, convergent/discriminant validity, and adherence to the distribution of BDI. Results: The BFMS had unsatisfactory measurement properties, the GDRS had acceptable reliability but other properties could not be completely testable; the JRS had satisfactory measurement properties but the scale did not accurately reflect the distribution of disability parameter (BDI) in the sample, and the BSRS had satisfactory measurement properties and also showed the best adherence to the distribution of BDI in the assessed sample. Conclusion: The comparison of the measurement properties of four rating scales to assess the motor state of the BSP in a large sample of patients from multiple sites showed that the GDRS should be used to simultaneously assess BSP and dystonia in other body parts, while the JRS (easier to use) and BSRS (better to discriminate severity) should be used to assess BSP alone.
Authors: Neil Aaronson; Jordi Alonso; Audrey Burnam; Kathleen N Lohr; Donald L Patrick; Edward Perrin; Ruth E Stein Journal: Qual Life Res Date: 2002-05 Impact factor: 4.147
Authors: Giovanni Defazio; Mark Hallett; Hyder A Jinnah; Glenn T Stebbins; Angelo F Gigante; Gina Ferrazzano; Antonella Conte; Giovanni Fabbrini; Alfredo Berardelli Journal: Mov Disord Date: 2015-04 Impact factor: 10.338
Authors: Michele Tinazzi; Roberto Erro; Marcello Mario Mascia; Marcello Esposito; Tommaso Ercoli; Gina Ferrazzano; Francesca Di Biasio; Roberta Pellicciari; Roberto Eleopra; Francesco Bono; Laura Bertolasi; Paolo Barone; Cesa Lorella Maria Scaglione; Antonio Pisani; Maria Concetta Altavista; Maria Sofia Cotelli; Roberto Ceravolo; Giovanni Cossu; Maurizio Zibetti; Mario Coletti Moja; Paolo Girlanda; Luca Maderna; Alberto Albanese; Martina Petracca; Luca Magistrelli; Salvatore Misceo; Brigida Minafra; Marcello Romano; Giovanna Maddalena Squintani; Nicola Modugno; Marco Aguggia; Daniela Cassano; Anna Castagna; Francesca Morgante; Alfredo Berardelli; Giovanni Defazio Journal: J Neural Transm (Vienna) Date: 2020-08-26 Impact factor: 3.575