Mohamed Laroussi Toumia1, Ahmed Amine Mohseni2, Mohamed Nabil Nessib2, Rim Boussetta2, Houda Yacoub-Youssef3, Sami Bouchoucha2. 1. Department of Pediatric Orthopaedic Surgery, Medical School of Tunis, Children's Hospital "Bechir HAMZA", University Tunis-El Manar, Tunis, Tunisia. Toumia.med.laroussi@gmail.com. 2. Department of Pediatric Orthopaedic Surgery, Medical School of Tunis, Children's Hospital "Bechir HAMZA", University Tunis-El Manar, Tunis, Tunisia. 3. Laboratory of Biomedical Genomics and Oncogenetics (LR16IPT05), Institut Pasteur de Tunis, Université Tunis El Manar, El Manar I, 2092, Tunis, Tunisia.
Abstract
PURPOSE: To study the results and complications of Traditional Growing Rods (TGR) for the treatment of Early-Onset Scoliosis (EOS) in patients with Ehlers-Danlos syndrome (EDS). METHODS: This is a retrospective study of patients with EDS treated for EOS between 2012 and 2018 by TGR. For each patient, we evaluated the evolution of the Cobb angle of the main coronal curve before the first surgery, postoperatively and at the last follow-up. We also noted every complication. RESULTS: Four patients have been evaluated. Age at the index surgery ranged from 3- to 6-year-old. All the patients had a Kyphoscoliosis. The preoperative Cobb angle of the main coronal curve ranged from 70° to 104°. Prior to surgery, a progressive correction of the spinal deformity by Halo-gravity traction was performed for all patients. One patient had several complications with a poor result after final fusion. Three patients did not sustain any complication and presented good results. Follow-up ranged from 3 to 8 years. For two of our patients, further lengthening procedures are still needed. CONCLUSIONS: TGR is a good surgical option for the treatment of EOS in EDS. A progressive preoperative correction is recommended. Anchor-related complications must be minimized in these patients with an important kyphosis. Level of evidence Level IV.
PURPOSE: To study the results and complications of Traditional Growing Rods (TGR) for the treatment of Early-Onset Scoliosis (EOS) in patients with Ehlers-Danlos syndrome (EDS). METHODS: This is a retrospective study of patients with EDS treated for EOS between 2012 and 2018 by TGR. For each patient, we evaluated the evolution of the Cobb angle of the main coronal curve before the first surgery, postoperatively and at the last follow-up. We also noted every complication. RESULTS: Four patients have been evaluated. Age at the index surgery ranged from 3- to 6-year-old. All the patients had a Kyphoscoliosis. The preoperative Cobb angle of the main coronal curve ranged from 70° to 104°. Prior to surgery, a progressive correction of the spinal deformity by Halo-gravity traction was performed for all patients. One patient had several complications with a poor result after final fusion. Three patients did not sustain any complication and presented good results. Follow-up ranged from 3 to 8 years. For two of our patients, further lengthening procedures are still needed. CONCLUSIONS: TGR is a good surgical option for the treatment of EOS in EDS. A progressive preoperative correction is recommended. Anchor-related complications must be minimized in these patients with an important kyphosis. Level of evidence Level IV.
Authors: Fransiska Malfait; Clair Francomano; Peter Byers; John Belmont; Britta Berglund; James Black; Lara Bloom; Jessica M Bowen; Angela F Brady; Nigel P Burrows; Marco Castori; Helen Cohen; Marina Colombi; Serwet Demirdas; Julie De Backer; Anne De Paepe; Sylvie Fournel-Gigleux; Michael Frank; Neeti Ghali; Cecilia Giunta; Rodney Grahame; Alan Hakim; Xavier Jeunemaitre; Diana Johnson; Birgit Juul-Kristensen; Ines Kapferer-Seebacher; Hanadi Kazkaz; Tomoki Kosho; Mark E Lavallee; Howard Levy; Roberto Mendoza-Londono; Melanie Pepin; F Michael Pope; Eyal Reinstein; Leema Robert; Marianne Rohrbach; Lynn Sanders; Glenda J Sobey; Tim Van Damme; Anthony Vandersteen; Caroline van Mourik; Nicol Voermans; Nigel Wheeldon; Johannes Zschocke; Brad Tinkle Journal: Am J Med Genet C Semin Med Genet Date: 2017-03 Impact factor: 3.908
Authors: Cecilia Giunta; Matthias Baumann; Christine Fauth; Uschi Lindert; Ebtesam M Abdalla; Angela F Brady; James Collins; Jahannaz Dastgir; Sandra Donkervoort; Neeti Ghali; Diana S Johnson; Ariana Kariminejad; Johannes Koch; Marius Kraenzlin; Nayana Lahiri; Bernarda Lozic; Adnan Y Manzur; Jenny E V Morton; Jacek Pilch; Rebecca C Pollitt; Gudrun Schreiber; Nora L Shannon; Glenda Sobey; Anthony Vandersteen; Fleur S van Dijk; Martina Witsch-Baumgartner; Johannes Zschocke; F Michael Pope; Carsten G Bönnemann; Marianne Rohrbach Journal: Genet Med Date: 2017-06-15 Impact factor: 8.822