Literature DB >> 36220985

Clinical and financial outcomes of per-oral endoscopic myotomy compared to laparoscopic heller myotomy for treatment of achalasia.

Lena Shally1, Kashif Saeed2, Derek Berglund2, Mark Dudash2, Katie Frank3, Vladan N Obradovic2, Anthony T Petrick2, David L Diehl4, Jon D Gabrielsen2, David M Parker2.   

Abstract

BACKGROUND: Previous studies analyzing short-term outcomes for per-oral endoscopic myotomy (POEM) have shown excellent clinical response rates and shorter operative times compared to laparoscopic Heller myotomy (LHM). Despite this, many payors have been slow to recognize POEM as a valid treatment option. Furthermore, comparative studies analyzing long-term outcomes are limited. This study compares perioperative and long-term outcomes, cost-effectiveness, and reimbursement for POEM and LHM at a single institution.
METHODS: Adult patients who underwent POEM or LHM between 2014 and 2021 and had complete preoperative data with at least one complete follow up, were retrospectively analyzed. Demographic data, success rate, operative time, myotomy length, length of stay, pre- and postoperative symptom scores, anti-reflux medication use, cost and reimbursement were compared.
RESULTS: 58 patients met inclusion with 25 undergoing LHM and 33 undergoing POEM. There were no significant differences in preoperative characteristics. Treatment success (Eckardt ≤ 3) for POEM and LHM was achieved by 88% and 76% of patients, respectively (p = 0.302). POEM patients had a shorter median operative time (106 min. vs. 145 min., p = 0.003) and longer median myotomy length (11 cm vs. 8 cm, p < 0.001). All LHM patients had a length of stay (LOS) ≥ 1 day vs. 51.5% for POEM patients (p < 0.001). Both groups showed improvements in dysphagia, heartburn, regurgitation, Eckardt score, GERD HRQL, RSI, and anti-reflux medication use. The improvement in dysphagia score was greater in patients undergoing POEM (2.30 vs 1.12, p = 0.003). Median hospital reimbursement was dramatically less for POEM ($3,658 vs. $14,152, p = 0.002), despite median hospital costs being significantly lower compared to LHM ($2,420 vs. $3,132, p = 0.029).
RESULTS: POEM is associated with a shorter operative time and LOS, longer myotomy length, and greater resolution of dysphagia compared to LHM. POEM costs are significantly less than LHM but is poorly reimbursed.
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Achalasia; Dysphagia; Laparoscopic Heller myotomy; Per-oral endoscopic myotomy; Symptomatic treatment

Year:  2022        PMID: 36220985     DOI: 10.1007/s00464-022-09652-6

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   3.453


  35 in total

1.  Per-oral endoscopic myotomy for achalasia. Are results comparable to laparoscopic Heller myotomy?

Authors:  Koshi Kumagai; Jon A Tsai; Anders Thorell; Lars Lundell; Bengt Håkanson
Journal:  Scand J Gastroenterol       Date:  2015-02-24       Impact factor: 2.423

Review 2.  Updated Systematic Review of Achalasia, with a Focus on POEM Therapy.

Authors:  Mitchell S Cappell; Stavros Nicholas Stavropoulos; David Friedel
Journal:  Dig Dis Sci       Date:  2019-08-27       Impact factor: 3.199

Review 3.  Peroral endoscopic myotomy (POEM) for treating esophageal motility disorders.

Authors:  Ian Wong; Simon Law
Journal:  Ann Transl Med       Date:  2017-04

4.  Long-term outcomes following POEM for non-achalasia motility disorders of the esophagus.

Authors:  Filippo Filicori; Christy M Dunst; Ahmed Sharata; Walaa F Abdelmoaty; Ahmed M Zihni; Kevin M Reavis; Steven R Demeester; Lee L Swanström
Journal:  Surg Endosc       Date:  2018-09-19       Impact factor: 4.584

5.  Pneumatic dilation versus laparoscopic Heller's myotomy for idiopathic achalasia.

Authors:  Guy E Boeckxstaens; Vito Annese; Stanislas Bruley des Varannes; Stanislas Chaussade; Mario Costantini; Antonello Cuttitta; J Ignasi Elizalde; Uberto Fumagalli; Marianne Gaudric; Wout O Rohof; André J Smout; Jan Tack; Aeilko H Zwinderman; Giovanni Zaninotto; Olivier R Busch
Journal:  N Engl J Med       Date:  2011-05-12       Impact factor: 91.245

6.  Laparoscopic Heller myotomy as the gold standard for treatment of achalasia.

Authors:  Peter Nau; David Rattner
Journal:  J Gastrointest Surg       Date:  2014-09-10       Impact factor: 3.452

7.  Long-term dysphagia resolution following POEM versus Heller myotomy for achalasia patients.

Authors:  Grace E Shea; Morgan K Johnson; Manasa Venkatesh; Sally A Jolles; Tyler M Prout; Amber L Shada; Jacob A Greenberg; Anne O Lidor; Luke M Funk
Journal:  Surg Endosc       Date:  2019-07-10       Impact factor: 4.584

8.  POEM for achalasia: endoscopic myotomy enters its golden age, and we are taking NOTES.

Authors:  Thomas M Runge; Yervant Ichkhanian; Mouen A Khashab
Journal:  Gastrointest Endosc       Date:  2020-05       Impact factor: 9.427

9.  Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia.

Authors:  Yuki B Werner; Bengt Hakanson; Jan Martinek; Alessandro Repici; Burkhard H A von Rahden; Albert J Bredenoord; Raf Bisschops; Helmut Messmann; Marius C Vollberg; Tania Noder; Jan F Kersten; Oliver Mann; Jakob Izbicki; Alexander Pazdro; Uberto Fumagalli; Riccardo Rosati; Christoph-Thomas Germer; Marlies P Schijven; Alice Emmermann; Daniel von Renteln; Paul Fockens; Guy Boeckxstaens; Thomas Rösch
Journal:  N Engl J Med       Date:  2019-12-05       Impact factor: 91.245

Review 10.  Endoscope-guided pneumatic dilation for treatment of esophageal achalasia.

Authors:  Seng-Kee Chuah; Keng-Liang Wu; Tsung-Hui Hu; Wei-Chen Tai; Chi-Sin Changchien
Journal:  World J Gastroenterol       Date:  2010-01-28       Impact factor: 5.742

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