Literature DB >> 36214864

Diagnostic delay stages and pre-diagnostic treatment in patients with suspected rheumatic diseases before special care consultation: results of a multicenter-based study.

Franziska Fuchs1,2, Harriet Morf1,2, Jacob Mohn1,2, Felix Mühlensiepen3, Yuriy Ignatyev3, Daniela Bohr1,2, Elizabeth Araujo1,2, Christina Bergmann1,2, David Simon1,2, Arnd Kleyer1,2, Wolfgang Vorbrüggen4,5, Andreas Ramming1,2, Jörg H W Distler1,2, Peter Bartz-Bazzanella5,6, Georg Schett1,2, Martin Welcker6,7, Axel J Hueber8,9, Johannes Knitza10,11.   

Abstract

Early and effective discrimination (triage) of patients with inflammatory rheumatic diseases (IRD) and other diseases (non-IRD) is essential for successful treatment and preventing damage. The aim of this study was to investigate diagnostic delays and pre-diagnosis treatment in patients newly presenting to rheumatology outpatient clinics. A total of 600 patients newly presenting to one university hospital and two non-academic centers were included. Time from onset of symptoms to rheumatology consultation "total delay" as well as medical treatment before consultation were recorded. Median time from symptom onset to rheumatologist appointment (total delay) was 30 weeks. Median time to online search, first physician appointment request and first physician appointment was 2, 4 and 5 weeks, respectively. Total delay was significantly shorter for IRD patients compared to non-IRD patients, 26 vs 35 weeks (p = 0.007). Only 17.7% of all patients and 22.9% of IRD patients had a delay of less than 12 weeks. Total delay was significantly lower in patients seen in non-academic centers compared to the university center, 20 vs 50 weeks (p < 0.0001). 32.2% of IRD patients received medical treatment that eased their symptoms prior to the rheumatology appointment. These findings highlight the persistent diagnostic delays in rheumatology; however, they also suggest that current triage strategies effectively lead to earlier appointments for IRD patients. Improvement of triage methods and pre-diagnosis treatment could decrease overall burden of disease in IRD patients.
© 2022. The Author(s).

Entities:  

Keywords:  Delayed diagnosis; Diagnostic delay; Health service research; Outcome research; Time to therapy; Triage

Year:  2022        PMID: 36214864     DOI: 10.1007/s00296-022-05223-z

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN: 0172-8172            Impact factor:   3.580


  22 in total

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Authors:  Michael P M van der Linden; Saskia le Cessie; Karim Raza; Diane van der Woude; Rachel Knevel; Tom W J Huizinga; Annette H M van der Helm-van Mil
Journal:  Arthritis Rheum       Date:  2010-12

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Authors:  Gerd R Burmester; Janet E Pope
Journal:  Lancet       Date:  2017-06-10       Impact factor: 79.321

Review 3.  [Specialist training quo vadis?]

Authors:  M Krusche; P Sewerin; A Kleyer; J Mucke; D Vossen; H Morf
Journal:  Z Rheumatol       Date:  2019-10       Impact factor: 1.372

4.  2016 update of the EULAR recommendations for the management of early arthritis.

Authors:  Bernard Combe; Robert Landewe; Claire I Daien; Charlotte Hua; Daniel Aletaha; Jose María Álvaro-Gracia; Margôt Bakkers; Nina Brodin; Gerd R Burmester; Catalin Codreanu; Richard Conway; Maxime Dougados; Paul Emery; Gianfranco Ferraccioli; Joao Fonseca; Karim Raza; Lucía Silva-Fernández; Josef S Smolen; Diana Skingle; Zoltan Szekanecz; Tore K Kvien; Annette van der Helm-van Mil; Ronald van Vollenhoven
Journal:  Ann Rheum Dis       Date:  2016-12-15       Impact factor: 19.103

5.  [Memorandum of the German Society for Rheumatology on the quality of treatment in rheumatology - Update 2016].

Authors:  A Zink; J Braun; E Gromnica-Ihle; D Krause; H J Lakomek; W Mau; U Müller-Ladner; J Rautenstrauch; C Specker; M Schneider
Journal:  Z Rheumatol       Date:  2017-04       Impact factor: 1.372

6.  [Diagnostic spectrum, treatment indication and symptom duration in initial referrals to the rheumatologist].

Authors:  G Westhoff; E Edelmann; J Kekow; A Zink
Journal:  Z Rheumatol       Date:  2010-12       Impact factor: 1.372

Review 7.  A systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis.

Authors:  Edith Villeneuve; Jackie L Nam; Mary J Bell; Christopher M Deighton; David T Felson; Johanna M Hazes; Iain B McInnes; Alan J Silman; Daniel H Solomon; Andrew E Thompson; Patience H P White; Vivian P Bykerk; Paul Emery
Journal:  Ann Rheum Dis       Date:  2012-04-24       Impact factor: 19.103

Review 8.  Window of opportunity in rheumatoid arthritis - definitions and supporting evidence: from old to new perspectives.

Authors:  Leonie E Burgers; Karim Raza; Annette H van der Helm-van Mil
Journal:  RMD Open       Date:  2019-04-03

9.  Delays between the onset of symptoms and first rheumatology consultation in patients with rheumatoid arthritis in the UK: an observational study.

Authors:  Rebecca Jayne Stack; Peter Nightingale; Clare Jinks; Karen Shaw; Sandy Herron-Marx; Rob Horne; Chris Deighton; Patrick Kiely; Christian Mallen; Karim Raza
Journal:  BMJ Open       Date:  2019-03-04       Impact factor: 2.692

10.  Interval between symptom onset and diagnosis among patients with autoimmune rheumatic diseases in a multi-ethnic Asian population.

Authors:  Ling Xiang; Andrea Hsiu Ling Low; Ying Ying Leung; Warren Fong; Mihir Gandhi; Sungwon Yoon; Tang Ching Lau; Dow Rhoon Koh; Julian Thumboo
Journal:  Int J Rheum Dis       Date:  2021-07-07       Impact factor: 2.454

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