Bernard Combe1, Robert Landewe2, Claire I Daien1, Charlotte Hua1, Daniel Aletaha3, Jose María Álvaro-Gracia4, Margôt Bakkers5, Nina Brodin6,7, Gerd R Burmester8, Catalin Codreanu9, Richard Conway10, Maxime Dougados11, Paul Emery12, Gianfranco Ferraccioli13, Joao Fonseca14,15, Karim Raza16,17, Lucía Silva-Fernández18, Josef S Smolen3, Diana Skingle5, Zoltan Szekanecz19, Tore K Kvien20, Annette van der Helm-van Mil21,22, Ronald van Vollenhoven23. 1. Rheumatology Department, Lapeyronie Hospital, Montpellier University, UMR 5535, Montpellier, France. 2. Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology Center, Amsterdam and Zuyderland Medical Centre, Heerlen, The Netherlands. 3. Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria. 4. Biological Therapies Unit, Servicio de Reumatología. Hospital Universitario de la Princesa, IIS-IP, Madrid, Spain. 5. EULAR Standing Committee of People with Arthritis/Rheumatism in Europe (PARE), Zurich, Switzerland. 6. Division of Physiotherapy, Department of Neurobiology Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden. 7. Department of Orthopaedics, Danderyd Hospital, Stockholm, Sweden. 8. Department of Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany. 9. Department of Rheumatology, Center for Rheumatic Diseases, University of Medicine and Pharmacy, Bucharest, Romania. 10. Department of Rheumatology, Centre for Arthritis and Rheumatic Diseases, St Vincent's University Hospital, Dublin Academic Medical Centre, Dublin, Ireland. 11. Medicine Faculty, APHP, Rheumatology B Department, Paris Descartes University, Cochin Hospital, Paris, France. 12. Leeds NIHR Musculoskeletal Biomedical Research Unit, LTHT, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK. 13. Fondazione Policlinico Gemelli Academic Hospital, Catholic University School of Medicine, Rome, Italy. 14. Rheumatology Department, Hospital de Santa Maria, Lisbon Academic Medical Centre, Lisbon. 15. Instituto de Medicina Molecular, Faculdade de Medicina Universidade de Lisboa, Portugal. 16. Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK. 17. Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK. 18. Rheumatology Department, Complexo Hospitalario Universitario de Ferrol, A Coruña, Spain. 19. Faculty of Medicine, Department of Rheumatology, University of Debrecen, Debrecen, Hungary. 20. Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway. 21. Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands. 22. Department of Rheumatology, Erasmus Medical Center, Rotterdam, The Netherlands. 23. Department of Clinical Immunology & Rheumatology, Academic Medical Center, Amsterdam, The Netherlands.
Abstract
OBJECTIVES: Since the 2007 recommendations for the management of early arthritis have been presented, considerable research has been published in the field of early arthritis, mandating an update of the 2007 European League Against Rheumatism (EULAR) recommendations for management of early arthritis. METHODS: In accordance with the 2014 EULAR Standardised Operating Procedures, the expert committee pursued an approach that was based on evidence in the literature and on expert opinion. The committee involved 20 rheumatologists, 2 patients and 1 healthcare professional representing 12 European countries. The group defined the focus of the expert committee and target population, formulated a definition of 'management' and selected the research questions. A systematic literature research (SLR) was performed by two fellows with the help of a skilled librarian. A set of draft recommendations was proposed on the basis of the research questions and the results of the SLR. For each recommendation, the categories of evidence were identified, the strength of recommendations was derived and the level of agreement was determined through a voting process. RESULTS: The updated recommendations comprise 3 overarching principles and 12 recommendations for managing early arthritis. The selected statements involve the recognition of arthritis, referral, diagnosis, prognostication, treatment (information, education, pharmacological and non-pharmacological interventions), monitoring and strategy. Eighteen items were identified as relevant for future research. CONCLUSIONS: These recommendations provide rheumatologists, general practitioners, healthcare professionals, patients and other stakeholders with an updated EULAR consensus on the entire management of early arthritis. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
OBJECTIVES: Since the 2007 recommendations for the management of early arthritis have been presented, considerable research has been published in the field of early arthritis, mandating an update of the 2007 European League Against Rheumatism (EULAR) recommendations for management of early arthritis. METHODS: In accordance with the 2014 EULAR Standardised Operating Procedures, the expert committee pursued an approach that was based on evidence in the literature and on expert opinion. The committee involved 20 rheumatologists, 2 patients and 1 healthcare professional representing 12 European countries. The group defined the focus of the expert committee and target population, formulated a definition of 'management' and selected the research questions. A systematic literature research (SLR) was performed by two fellows with the help of a skilled librarian. A set of draft recommendations was proposed on the basis of the research questions and the results of the SLR. For each recommendation, the categories of evidence were identified, the strength of recommendations was derived and the level of agreement was determined through a voting process. RESULTS: The updated recommendations comprise 3 overarching principles and 12 recommendations for managing early arthritis. The selected statements involve the recognition of arthritis, referral, diagnosis, prognostication, treatment (information, education, pharmacological and non-pharmacological interventions), monitoring and strategy. Eighteen items were identified as relevant for future research. CONCLUSIONS: These recommendations provide rheumatologists, general practitioners, healthcare professionals, patients and other stakeholders with an updated EULAR consensus on the entire management of early arthritis. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Authors: K Benesova; H-M Lorenz; V Lion; A Voigt; A Krause; O Sander; M Schneider; M Feuchtenberger; A Nigg; J Leipe; S Briem; E Tiessen; F Haas; M Rihl; D Meyer-Olson; X Baraliakos; J Braun; A Schwarting; M Dreher; T Witte; G Assmann; K Hoeper; R E Schmidt; P Bartz-Bazzanella; M Gaubitz; C Specker Journal: Z Rheumatol Date: 2019-10 Impact factor: 1.372
Authors: Ana María Ortiz; Lucía Silva Fernández; Virginia Villaverde; Miguel Ángel Abad; José Ramón Maneiro; Gloria Candelas; Susana Gómez; Mónica Valderrama; María Montoro Journal: Rheumatol Int Date: 2020-10-20 Impact factor: 2.631