Zizhen Wang1,2, Haowen Ma3, Yu Zhang1,2, Yifei Yuan1,2, Yan Liu1,2, Yueguo Chen4,5. 1. Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China. 2. Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China. 3. Peking University Health Science Center, 38 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China. 4. Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China. chenyueguo@263.net. 5. Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China. chenyueguo@263.net.
Abstract
INTRODUCTION: This study evaluated the changes and explored influential factors in the anterior chamber after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) on the basis of patients with different degrees of myopia, refractive status, and age. METHODS: Patients underwent uneventful FS-LASIK for the treatment of ametropia. All patients with myopia were classified into a low age group (18-40 years) or high age group (> 40 years). Patients in the low age group (18-40 years) were subdivided into myopia and hyperopia groups. According to the preoperative spherical equivalent values, the myopia group was further divided into low myopia, moderate myopia, and high myopia groups. We measured the magnitude of anterior chamber depth (ACD), angle (ACA), volume (ACV), lens rise, central corneal thickness (CCT), and mean pupil power (MPP) of all patients using Sirius (version 3.2, CSO, Italy) before and 3 months post operation. RESULTS: A total of 140 eyes of 87 patients were evaluated. The magnitudes of ACD, ACA, and ACV decreased significantly postoperatively in both low age (P < 0.001, P < 0.001, P < 0.001, respectively) and high age group (P < 0.001, P < 0.001, P < 0.001, respectively) of patients with myopia, while an increasing tendency of ACD (2.85 ± 0.38 mm preoperatively vs 2.89 ± 0.09 mm postoperatively) and ACA (39.16° ± 7.30° preoperatively vs 39.37° ± 7.68° postoperatively) was found in hyperopia. There was no correlation between different degrees of myopia and the changes in the anterior chamber. CONCLUSIONS: Anterior chamber parameters decreased significantly and approximately in the same degree in low and high age groups postoperatively, while an increasing tendency of ACD and ACA was found in hyperopia, indicating that it is probably a corneal magnification effect that influences changes in the anterior chamber.
INTRODUCTION: This study evaluated the changes and explored influential factors in the anterior chamber after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) on the basis of patients with different degrees of myopia, refractive status, and age. METHODS: Patients underwent uneventful FS-LASIK for the treatment of ametropia. All patients with myopia were classified into a low age group (18-40 years) or high age group (> 40 years). Patients in the low age group (18-40 years) were subdivided into myopia and hyperopia groups. According to the preoperative spherical equivalent values, the myopia group was further divided into low myopia, moderate myopia, and high myopia groups. We measured the magnitude of anterior chamber depth (ACD), angle (ACA), volume (ACV), lens rise, central corneal thickness (CCT), and mean pupil power (MPP) of all patients using Sirius (version 3.2, CSO, Italy) before and 3 months post operation. RESULTS: A total of 140 eyes of 87 patients were evaluated. The magnitudes of ACD, ACA, and ACV decreased significantly postoperatively in both low age (P < 0.001, P < 0.001, P < 0.001, respectively) and high age group (P < 0.001, P < 0.001, P < 0.001, respectively) of patients with myopia, while an increasing tendency of ACD (2.85 ± 0.38 mm preoperatively vs 2.89 ± 0.09 mm postoperatively) and ACA (39.16° ± 7.30° preoperatively vs 39.37° ± 7.68° postoperatively) was found in hyperopia. There was no correlation between different degrees of myopia and the changes in the anterior chamber. CONCLUSIONS: Anterior chamber parameters decreased significantly and approximately in the same degree in low and high age groups postoperatively, while an increasing tendency of ACD and ACA was found in hyperopia, indicating that it is probably a corneal magnification effect that influences changes in the anterior chamber.